Evidence map›Paper›PMID 42436221›Full record

ArticleCommunications biology2026

Astrocyte store released calcium modulates structural synapse development and circuit output in the visual system.

Gillian Imrie, Jordan Mar, Madison B Gray, Tatiana Quiceno, Isabella Farhy-Tselnicker

Abstract read
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In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Gillian ImrieDepartment of Biology, Texas A&M University, College Station, TX, USA.
Jordan MarTexas A&M Institute for Neuroscience (TAMIN), Texas A&M University, College Station, TX, USA.
Madison B GrayDepartment of Biology, Texas A&M University, College Station, TX, USA.
Tatiana QuicenoDepartment of Biology, Texas A&M University, College Station, TX, USA.
Isabella Farhy-TselnickerDepartment of Biology, Texas A&M University, College Station, TX, USA. ifarhy@bio.tamu.edu.ORCID http://orcid.org/0000-0002-3733-7120

Funding

Regulation of Synaptic Rhythmicity by Astrocytic ClockR01NS133047 · NINDS · TEXAS A&M UNIVERSITY · PI Isabella Farhy · 2023 to 2026
$1.5M
NINDS NIH HHS R01 NS133047U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS133047U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS133047
6 · The paper itself

Abstract

Astrocytes, a major class of glial cells, are critical regulators of neuronal synapse development and function. Deficits in astrocyte-synapse interactions are implicated in various neurological disorders, yet the precise mechanisms by which astrocytes guide synapse formation and maturation during development remain poorly understood. A key astrocytic mechanism for integrating both extrinsic (e.g., neuronal) and intrinsic signals is the IP3-mediated release of intracellular calcium (Ca

Identifiers

PMID42436221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.