Evidence map›Paper›PMID 42436217›Full record

ArticleScientific reports2026

BabyFlow: 3D modeling of realistic and expressive infant faces.

Antonia Alomar, Mireia Masias, Marius George Linguraru, Federico M Sukno, Gemma Piella

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antonia AlomarDepartment of Engineering, Universitat Pompeu Fabra, 122-140 Tànger, Barcelona, 08018, Spain. antonia.alomar@upf.edu.
Mireia MasiasDepartment of Engineering, Universitat Pompeu Fabra, 122-140 Tànger, Barcelona, 08018, Spain.
Marius George LinguraruSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, 111 Michigan Ave NW, Washington, 20010, DC, USA.
Federico M SuknoDepartment of Engineering, Universitat Pompeu Fabra, 122-140 Tànger, Barcelona, 08018, Spain.
Gemma PiellaDepartment of Engineering, Universitat Pompeu Fabra, 122-140 Tànger, Barcelona, 08018, Spain.

Funding

Eunice Kennedy Shriver National Institute of Child Health and Human Development R42 HD08171203Ministerio de Ciencia e Innovación PRE2021-097544
6 · The paper itself

Abstract

Early detection of developmental disorders can be aided by analyzing infant craniofacial morphology, but modeling infant faces is challenging due to limited data and frequent spontaneous expressions. We introduce BabyFlow, a generative AI model that disentangles facial identity and expression, enabling independent control over both. Using normalizing flows, BabyFlow learns flexible, probabilistic representations that capture the complex, non-linear variability of expressive infant faces without restrictive linear assumptions. To address scarce and uncontrolled expressive data, we perform cross-age expression transfer, adapting expressions from adult 3D scans to enrich infant datasets with realistic and systematic expressive variants. As a result, BabyFlow improves 3D reconstruction accuracy, particularly in highly expressive regions such as the mouth, eyes, and nose, and supports synthesis and modification of infant expressions while preserving identity. However, the current model is trained on a relatively small cohort of craniofacially unaffected infants, which may limit generalization to pathological morphologies. Additionally, integrating BabyFlow with diffusion models offers a promising direction for data synthesis, as it could serve as a conditioning mechanism for generating expressive and realistic 2D infant images. Further evaluation is needed to assess image realism, 3D-2D geometric consistency, robustness, and potential ethical and bias-related concerns.

Indexed as

DisentanglementFacial expressionGenerative AIInfant face modelingNormalizing flowShape morphology

Identifiers

PMID42436217
PMCPMC13654800

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.