Evidence map›Paper›PMID 42436145›Full record

ArticleNature communications2026

Super-resolution atlas of SARS-CoV-2 infection reveals protease-dependent organelle maturation, dsRNA landscapes, and intracellular structural proteins.

Leonid Andronov, Mengting Han, Ashwin Balaji, Yanyu Zhu, Lei S Qi, W E Moerner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Organization of Myosin H in the Apical Complex ofbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Leonid Andronov *Department of Chemistry, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-4213-5363
Mengting Han *Department of Bioengineering, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-6253-2470
Ashwin BalajiDepartment of Chemistry, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-0075-4203
Yanyu ZhuDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-8681-976X
Lei S QiDepartment of Bioengineering, Stanford University, Stanford, CA, USA. sqi@stanford.edu.ORCID http://orcid.org/0000-0002-3965-3223
W E MoernerDepartment of Chemistry, Stanford University, Stanford, CA, USA. wmoerner@stanford.edu.ORCID http://orcid.org/0000-0002-2830-209X

Funding

Single-Molecule Imaging for Cell Biology and Super-Resolution MicroscopyR35GM118067 · NIGMS · STANFORD UNIVERSITY · PI MOERNER, WILLIAM E · 2016 to 2025
$6.2M
NIGMS NIH HHS R35 GM118067U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35-GM118067
6 · The paper itself

Abstract

Coronaviral replication depends on double-membrane vesicles (DMVs), yet where polyprotein processing occurs and how replication organelles mature remain unresolved. We built a multi-color super-resolution atlas of SARS-CoV-2 RNA, non-structural and structural proteins in infected human cells, combining 3D single-molecule localization with radial and angular pair-correlation analysis. The atlas uncovers fundamental spatial principles. First, nsp5 (3CL

Indexed as

COVID-19OrganellesRNA, Double-StrandedRNA, ViralSARS-CoV-2HumansPeptide HydrolasesRNA ReplicationViral Nonstructural ProteinsVirus ReplicationPeptide HydrolasesRNA, Double-StrandedRNA, ViralViral Nonstructural Proteins

Identifiers

PMID42436145
PMCPMC13487147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.