Evidence map›Paper›PMID 42435264›Full record

ArticleAntonie van Leeuwenhoek2026

Genomic insights into Mycobacterium cavoris sp. nov., related to Mycobacterium terrae complex isolated from the oral cavity of a healthy adult.

Varsha Chauhan, Kamal Shrivastava, Pradeep Kumar, Sakshi Anand, Chanchal Kumar, Anupriya Singh, Swati Kathait, Sanjay Kumar, Mandira Varma-Basil

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Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Varsha ChauhanDepartment of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.ORCID http://orcid.org/0000-0002-1234-1932
Kamal ShrivastavaDepartment of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.ORCID http://orcid.org/0000-0002-8904-5859
Pradeep KumarDepartment of Microbiology, Maharshi Dayanand University, Rohtak, India.ORCID http://orcid.org/0000-0002-3697-9981
Sakshi AnandDepartment of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.ORCID http://orcid.org/0000-0001-8221-9441
Chanchal KumarDepartment of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.ORCID http://orcid.org/0000-0003-1706-2729
Anupriya SinghDepartment of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.ORCID http://orcid.org/0000-0002-5376-3306
Swati KathaitDepartment of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.ORCID http://orcid.org/0009-0009-4858-6016
Sanjay KumarDepartment of Microbiology, Maharshi Dayanand University, Rohtak, India.ORCID http://orcid.org/0000-0002-4302-3777
Mandira Varma-BasilDepartment of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India. mandirav@rediffmail.com.ORCID https://orcid.org/0000-0001-5562-015X

Funding

Indian Council of Medical Research 5/3/8/6/ITR-F/2018-ITRIndian Council of Medical Research CMR, Fellowship/TB/1/2020/ECD-1Indian Council of Medical Research ICMR/5/8/5/22/2019 ECD-I
6 · The paper itself

Abstract

We report the genome sequence of a novel species of nontuberculous mycobacterium (NTM) belonging to the Mycobacterium terrae complex (MTC). The strain SVM_VP21 was isolated from the mouthwash sample of a healthy human adult residing in Delhi, India. The strain exhibited smooth, cream-coloured colonies on Lowenstein Jensen (LJ) medium after 2 weeks of incubation and could not be identified by Hain's Genotype Mycobacterium CM/AS line probe assay. Whole genome sequencing (WGS) of SVM_VP21 was performed using Illumina NovaSeq 6000 platform for final identification. The whole genome sequence was assembled using Shovill. Gene annotation was performed by Rapid Annotation using Subsystem Technology (RAST) and Prokaryotic Genome Annotation Pipeline (PGAP). The genome of 4,882,418 bp exhibited 67.3% GC content, 59 contigs, 4557 genes and 4502 coding sequences. The genome also encoded four rRNAs, 48 tRNAs, three non-coding RNAs and 177 pseudo genes. BLASTn analysis of the 16S rRNA and hsp65 gene sequences retrieved by WGS showed 100% and 95% identity to M. heraklionense, respectively. AutoMLST showed 93.5% average nucleotide identity of SVM_VP21 to M. virginiense. Digital DNA-DNA Hybridization, finally, identified SVM_VP21 as a novel species of the M. terrae complex. The name Mycobacterium cavoris sp. nov. is proposed for the strain in reference to its isolation from the oral cavity. The data presented here would help in understanding the novel species, which though obtained from a healthy individual in this study, may be a potential pathogen.

Indexed as

Genome, BacterialMouthMycobacteriumNontuberculous MycobacteriaBacterial ProteinsBase CompositionDNA, BacterialGenomicsHumansIndiaPhylogenyRNA, Ribosomal, 16SSequence Analysis, DNAWhole Genome SequencingBacterial ProteinsDNA, BacterialRNA, Ribosomal, 16SCommensal floraMycobacterium cavoris sp. nov.Mycobacterium heraklionenseMycobacterium terrae complexNontuberculous mycobacteriaWhole genome sequencing

Identifiers

PMID42435264

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.