ArticleJACC. Case reports2026
Large Progressive Right Coronary Artery Aneurysm Secondary to IgG4 Disease.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
backgroundCoronary artery aneurysm is a rare but well recognized manifestation of immunoglobulin G4 (IgG4)-related disease, with a paucity of data to guide its management. CASE SUMMARY: A 62-year-old man with known IgG4-related disease diagnosed 2 years prior presented for routine clinic follow-up. Despite being asymptomatic and remaining in serologic remission, imaging demonstrated marked progression of a large right coronary artery aneurysm measuring 62 mm × 72 mm. Given prohibitive operative risks, immunosuppressive therapy was intensified with close imaging follow-up. DISCUSSION: Published experience with IgG4-related coronary artery aneurysm is limited to small case series, with highly variable management strategies and outcomes. To the authors' knowledge, this case represents the largest conservatively managed IgG4-related coronary aneurysm reported. TAKE HOME MESSAGES: IgG4-related coronary aneurysms may progress silently with disassociation between serologic remission and disease progression on imaging. Multidisciplinary decision-making is critical to optimize outcomes in this high-risk condition, particularly with regard to the surveillance strategy in patients who otherwise achieve biochemical remission.
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