Evidence map›Paper›PMID 42434858›Full record

ArticleAnnals of medicine2026

Transcutaneous auricular vagus nerve stimulation for postoperative nausea and vomiting in gynecological laparoscopic surgery: a randomized controlled trial protocol.

Peilin Li, Lijun Fan, Qingcai Chen, Xiaoming Jia, Guowang Yang, Guangchao Zhang

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peilin LiDepartment of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0009-0004-7434-564X
Lijun FanDepartment of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0001-5947-1171
Qingcai ChenDepartment of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xiaoming JiaDepartment of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Guowang YangDepartment of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0009-0001-2641-8435
Guangchao ZhangDepartment of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-8298-0422

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPostoperative nausea and vomiting (PONV) are common adverse events following gynecological laparoscopic surgery. This study aims to evaluate the efficacy of transcutaneous auricular vagus nerve stimulation in reducing the incidence of PONV within 24 h after gynecological laparoscopic surgery. METHODS AND ANALYSIS: This single-center, prospective, double-blinded, randomized and sham-controlled trial will enroll 200 patients scheduled for gynecological laparoscopic surgery. Participants will be randomized in a 1:1 ratio to either the taVNS group or the sham group. The taVNS group will receive electrical stimulation lasting for 30 min after anesthesia induction. Sham group will not provide stimulation. The primary endpoint is the incidence of PONV within the first 24 h after surgery. Secondary endpoints include the severity of PONV, the usage of rescue antiemetics and 5-point Likert satisfaction scale. Exploratory endpoints include consumption of opioids and heart rate variability within 24 h after surgery. DISCUSSION: The results of study will provide key evidence on the efficacy and safety of intraoperative taVNS for preventing PONV after gynecologic laparoscopic surgery.Trial registration: Chinese Clinical Trial Registry (registration No. ChiCTR2600120159; registered on March 10, 2026).

Indexed as

Gynecologic Surgical ProceduresLaparoscopyPostoperative Nausea and VomitingTranscutaneous Electric Nerve StimulationVagus Nerve StimulationAdultAntiemeticsDouble-Blind MethodFemaleHumansMiddle AgedProspective StudiesRandomized Controlled Trials as TopicTreatment OutcomeYoung AdultAntiemeticsgynecological laparoscopic surgerypostoperative nausea and vomitingTranscutaneous auricular vagus nerve stimulation

Identifiers

PMID42434858
PMCPMC13371485

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.