ArticleFrontiers in oncology2026
Intravoxel incoherent motion combined with conventional MRI for the differentiation of benign, intermediate, and malignant fibrous soft-tissue tumors.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Fibroblastic/myofibroblastic tumors are among the most common soft-tissue tumors (STTs) encountered clinically. Several magnetic resonance imaging (MRI) features associated with malignant tumors overlap with benign tumors, making differential diagnosis challenging. Intravoxel incoherent motion (IVIM) is a valuable MRI technique for differentiating various tumors. This study aims to evaluate the abilities of conventional MRI and IVIM in differentiating benign, intermediate, and malignant fibrous STTs. Methods: Fifty-five patients with fibrous STTs were prospectively enrolled, comprising 18 benign, 18 intermediate, and 19 malignant cases. All the patients underwent MRI examinations including IVIM. Conventional MRI signs and standard-apparent diffusion coefficient (ADC), true diffusion coefficient (D), pseudo-diffusion coefficient (D Results: Malignant tumors had higher heterogeneity on T2WI ( Conclusion: IVIM diffusion parameters differentiated benign, intermediate, and malignant fibrous STTs and can complement conventional MRI signs.
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