Evidence map›Paper›PMID 42434613›Full record

ArticleJournal of toxicology2026

Comparative Evaluation of Urine, Sputum, and BALF for Human Microplastic Exposure Monitoring Using a Multicriteria Decision Framework.

Neamatollah Jaafarzadeh Haghighi Fard, Faezeh Jahedi, Afshin Takdastan, Mehdi Ahmadi, Maryam Haddadzadeh Shoushtari

Abstract read
In one paragraph

Article in Journal of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Neamatollah Jaafarzadeh Haghighi FardEnvironmental Technologies Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, ajums.ac.ir.ORCID https://orcid.org/0000-0003-1172-4277
Faezeh JahediEnvironmental Technologies Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, ajums.ac.ir.ORCID https://orcid.org/0000-0002-2744-5101
Afshin TakdastanEnvironmental Technologies Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, ajums.ac.ir.ORCID https://orcid.org/0000-0002-0419-1698
Mehdi AhmadiEnvironmental Technologies Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, ajums.ac.ir.ORCID https://orcid.org/0000-0002-9227-7562
Maryam Haddadzadeh ShoushtariAir Pollution and Respiratory Disease Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, ajums.ac.ir.ORCID https://orcid.org/0000-0001-9300-9810

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microplastic (MP) contamination in human biological systems has become a global health concern. However, the selection of the most suitable matrix for biomonitoring remains an open area of investigation. This study evaluates three biological matrices-urine, sputum, and bronchoalveolar lavage fluid (BALF)-for their suitability in MP detection and monitoring. Using data collated from a recent observational study (30 patients) and peer-reviewed literature, we assessed detection sensitivity, polymer diversity, sample availability, and practical feasibility via a multicriteria decision analysis (MCDA) framework inspired by the analytic hierarchy process (AHP). Results showed that sputum exhibited the highest median MP concentration (9.4 particles/mL) and BALF showed the greatest polymer diversity (6 polymer types), while urine showed the lowest levels (2.7 particles/mL). The composite MCDA scores ranked urine highest (26/35) for population studies due to its noninvasiveness and reproducibility, followed by sputum (25/35) for respiratory exposure assessment and BALF (21/35) for deep-lung mechanistic studies. We conclude that a matrix-specific strategy is essential for advancing human MP biomonitoring.

Indexed as

AHPBALFbiomonitoringMCDAmicroplasticssputumurine

Identifiers

PMID42434613
PMCPMC13351611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.