Evidence map›Paper›PMID 42434562›Full record

ReviewFrontiers in microbiology2026

Advances in gene editing tools for four typical Gram-positive bacteria.

Zishan Liang, Zhengyu Li, Chunming Li, Yongqing Zhao, Junlin Liu, Jiao Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zishan LiangBiology Engineering College, Northwest Minzu University, Lanzhou, China.
Zhengyu LiBiology Engineering College, Northwest Minzu University, Lanzhou, China.
Chunming LiBiology Engineering College, Northwest Minzu University, Lanzhou, China.
Yongqing ZhaoBiology Engineering College, Northwest Minzu University, Lanzhou, China.
Junlin LiuBiology Engineering College, Northwest Minzu University, Lanzhou, China.
Jiao ZhangBiology Engineering College, Northwest Minzu University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gram-positive bacteria serve as important chassis microorganisms in synthetic biology, industrial fermentation, and probiotic development. The rapid advancement of gene editing technologies has provided critical technical support for the iterative construction and functional validation of engineered strains. However, due to factors such as cell wall structure, differences in genetic backgrounds, and tool compatibility, the development and editing efficiency of gene editing systems for Gram-positive bacteria still face many challenges. This review focuses on four representative Gram-positive bacterial species-

Indexed as

Bacillus subtilisCorynebium glutamicumCRISPR-CasLactobacillus plantarumLactococcus lactis

Identifiers

PMID42434562
PMCPMC13350027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.