Evidence map›Paper›PMID 42434539›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2026

A Case of Cala Trio-Induced Glossopharyngeal Neuralgia in a Patient with Essential Tremor and Idiopathic Parkinson's Disease.

Moriah R Arnold, Amie L Hiller

Erratum issuedAbstract readCase Reports
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Moriah R ArnoldMedical Scientist Training Program, Oregon Health and Science University, Portland, OR, USA.ORCID 0000-0002-5916-7978
Amie L HillerNeurology Department, Oregon Health and Science University, Portland, OR, USA.ORCID 0000-0001-5912-6941

Funding

Medical Scientist Training Program of Oregon Health & Science UniversityT32GM109835 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI JACOBY, DAVID B · 2016 to 2020
$1.1M
The role of alpha-synuclein in nucleolar DNA double-strand break repair and cellular senescenceF30AG082406 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Moriah Rebecca Arnold · 2023 to 2026
$216k
NIA NIH HHS F30 AG082406NIGMS NIH HHS T32 GM109835
6 · The paper itself

Abstract

Background: Cala Trio is a wrist-worn transcutaneous afferent patterned stimulation (TAPS) device for essential tremor (ET), delivering high-frequency stimulation to the median and radial nerves. Case Report: We report the first case of glossopharyngeal neuralgia (GPN) associated with Cala Trio initiation in a 69-year-old male with ET and Parkinson's disease, with prior GPN. Throat spasms triggered by swallowing and coughing began after initiation on two trials and resolved with discontinuation; evaluation was unrevealing. Discussion: We review TAPS mechanisms, GPN neuroanatomy, and circuit-level links between peripheral nerve stimulation and brainstem cranial nerve hyperexcitability, highlighting a novel adverse event and need for caution in patients with prior GPN. Highlights: We report the first case of glossopharyngeal neuralgia associated with Cala Trio TAPS therapy in a patient with essential tremor and Parkinson's disease. Symptoms were temporally linked to device use and resolved upon discontinuation, suggesting a reversible neuromodulation-related effect and expanding the safety profile of peripheral tremor therapies.

Indexed as

Essential TremorGlossopharyngeal Nerve DiseasesParkinson DiseaseTranscutaneous Electric Nerve StimulationAgedHumansMaleEssential tremorGlossopharyngeal neuralgiaNeuromodulationParkinson’s DiseaseTranscutaneous afferent patterned stimulation

Identifiers

PMID42434539
PMCPMC13353091

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.