One-step selection of high-affinity COP1 aptamers.

Lihong Song, Tiantian Zhou, Miqi Xu, Kaiqiang Qian, Xing Wang Deng, Qingqing Wu, Jun-Jie Ling

Abstract readLetter

In one paragraph

Article in aBIOTECH, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lihong SongSchool of Life Sciences, National Engineering Laboratory of Crop Stress Resistance Breeding, Anhui Agricultural University, Hefei, 230036, China.

Tiantian ZhouSchool of Life Sciences, National Engineering Laboratory of Crop Stress Resistance Breeding, Anhui Agricultural University, Hefei, 230036, China.

Miqi XuSchool of Life Sciences, National Engineering Laboratory of Crop Stress Resistance Breeding, Anhui Agricultural University, Hefei, 230036, China.

Kaiqiang QianSchool of Life Sciences, National Engineering Laboratory of Crop Stress Resistance Breeding, Anhui Agricultural University, Hefei, 230036, China.

Xing Wang DengState Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences at Weifang, Weifang, 261000, China.

Qingqing WuNational Engineering Laboratory of Crop Stress Resistance Breeding, Anhui Agricultural University, Bio-breeding Laboratory of Anhui Province, Hefei, 230036, China.

Jun-Jie LingSchool of Life Sciences, National Engineering Laboratory of Crop Stress Resistance Breeding, Anhui Agricultural University, Hefei, 230036, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aptamers are single-stranded DNA or RNA molecules that specifically bind to a wide range of target molecules with high affinity, making them powerful tools for synthetic biology. Traditional aptamer selection via Systematic Evolution of Ligands by Exponential Enrichment (SELEX) is labor-intensive and prone to nonspecific binding. To address these issues, we developed the Bead-based One-Step aptamer Selection (BOSS) method. As proof of concept, we used this method to target

Indexed as

AptamerCOP1ELONAOne-step selectionPlant synthetic biology

Identifiers

PMID42434511

DOI10.1016/j.abiote.2026.100060

PMCPMC13351135

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.