Evidence map›Paper›PMID 42434423›Full record

ArticleFrontiers in cellular and infection microbiology2026

Oral health status and subgingival microbiota in children with juvenile idiopathic arthritis.

Ceyhun Açarı, Yavuz Oktay, Gülser Kılınç, Leman Binokay, Serkan Türkuçar, Hatice Adıgüzel Dundar, Tutku Yaraş, Pelin Teke Kısa, Gökhan Karakülah, Nur Arslan and 2 more

Abstract read
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Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ceyhun AçarıPediatric Rheumatology, Inonu University, Malatya, Türkiye.
Yavuz OktayIzmir Biomedicine and Genom Center-IBG, Izmir, Türkiye.
Gülser KılınçDepartment of Children's Dentistry, Dokuz Eylul University, Izmir, Türkiye.
Leman BinokayIzmir Biomedicine and Genom Center-IBG, Izmir, Türkiye.
Serkan TürkuçarPediatric Rheumatology, Pamukkale University, Denizli, Türkiye.
Hatice Adıgüzel DundarPediatric Rheumatology, Behcet Uz Children's Hospital, Izmir, Türkiye.
Tutku YaraşIzmir Biomedicine and Genom Center-IBG, Izmir, Türkiye.
Pelin Teke KısaPediatric Metabolism and Nutrition, Dokuz Eylul University, Izmir, Türkiye.
Gökhan KarakülahIzmir Biomedicine and Genom Center-IBG, Izmir, Türkiye.
Nur ArslanPediatric Metabolism and Nutrition, Dokuz Eylul University, Izmir, Türkiye.
Mehmet Ali ÖktemDepartment of Microbiology, Dokuz Eylul University, Izmir, Türkiye.
Şevket Erbil ÜnsalPediatric Rheumatology, Dokuz Eylul University, Izmir, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to compare the oral and dental health status and the oral microbiota of patients with juvenile idiopathic arthritis (JIA) with those of healthy children. Methods: The 60 patients with JIA and 26 healthy children were included in the study. Decayed, missing, filled teeth index (DMFT/dmft), oral hygiene index (OHI), gingival index (GI), and papillary bleeding (PB) index analyses were performed for the permanent and deciduous teeth of the patients in the pediatric dental clinic. Subgingival plaque samples were taken from the gingival groove and tooth surface with a sterile swab and stored in a -80C freezer. Following the DNA isolation, the analysis of microbiota content was performed by 16S rRNA gene sequencing method. Results: The oral hygiene index (p=0.045), debris index (p=0.000), gingival index (p=0.001), and papillary bleeding index (p=0.002) were significantly higher in the patient group than in the control group. Oral microbiome analysis found no significant difference in alpha and beta diversity between the groups. Conclusions: In our study, The oral hygiene index (OHI) value, debris index (DI), and PBI were significantly higher in the patient group compared to the control group. Some bacteria such as

Indexed as

Arthritis, JuvenileGingivaMicrobiotaOral HealthAdolescentBacteriaChildChild, PreschoolDental PlaqueDNA, BacterialFemaleHumansMaleOral Hygiene IndexPeriodontal IndexRNA, Ribosomal, 16SDNA, BacterialRNA, Ribosomal, 16Sjuvenile idiopathic arthritisoral healthoral microbiotapeptostreptococcusperiodontitisporphyromonas

Identifiers

PMID42434423
PMCPMC13350034

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.