Evidence map›Paper›PMID 42434421›Full record

ArticleFrontiers in cellular and infection microbiology2026

Systemic serological signatures and novel biomarker CST4 link CagA-positive

Chonghe Xu, Shuping Lu, Shulei Zhang, Miaosu Chang, Shuo Zhang, Wei Xu, Mei Zhu

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chonghe Xu *School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Shuping Lu *Department of Clinical Laboratory, The Fourth Affiliated Hospital (Affiliated Chaohu Hospital) of Anhui Medical University, Chaohu, Anhui, China.
Shulei ZhangDepartment of Clinical Laboratory, The Fourth Affiliated Hospital (Affiliated Chaohu Hospital) of Anhui Medical University, Chaohu, Anhui, China.
Miaosu ChangDepartment of Clinical Laboratory, The Fourth Affiliated Hospital (Affiliated Chaohu Hospital) of Anhui Medical University, Chaohu, Anhui, China.
Shuo ZhangDepartment of Clinical Laboratory, The Fourth Affiliated Hospital (Affiliated Chaohu Hospital) of Anhui Medical University, Chaohu, Anhui, China.
Wei XuDepartment of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Mei ZhuDepartment of Clinical Laboratory, The Fourth Affiliated Hospital (Affiliated Chaohu Hospital) of Anhui Medical University, Chaohu, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Methods: This retrospective study enrolled 565 participants who underwent bidirectional endoscopy with histopathological confirmation. Results: CagA-positive infection, particularly the CagA Conclusion: CagA-positive

Indexed as

Antigens, BacterialBacterial ProteinsBiomarkersHelicobacter InfectionsHelicobacter pyloriAdultAgedFemaleHumansMaleMiddle AgedNomogramsRetrospective StudiesVirulence FactorsAntigens, BacterialBacterial ProteinsBiomarkerscagA protein, Helicobacter pyloriVacA protein, Helicobacter pyloriVirulence FactorsCagAcystatin 4Helicobacter pylorinomogramrisk predictionserological markersvirulence factors

Identifiers

PMID42434421
PMCPMC13350065

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.