ArticleFrontiers in endocrinology2026
Functional and clinical evidence for two novel heterozygous
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Introduction: Recurrent pregnancy loss (RPL) is a common reproductive disorder with largely unexplained etiology. Premature chromatid separation (PCS), a cytogenetic manifestation of chromosomal instability, is linked to spindle assembly checkpoint (SAC) dysfunction. While biallelic Methods: Here, we investigated two unrelated families with unexplained RPL. Chromosomal microarray analysis of six miscarriage specimens revealed random aneuploidies. Whole-exome sequencing identified two novel heterozygous Results: Two novel heterozygous Discussion: These findings provide the first clinical evidence suggesting that heterozygous
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