Evidence map›Paper›PMID 42434209›Full record

ReviewJournal of clinical and experimental dentistry2026

Fatigue Survival and Biomechanical Behavior of Two-piece Titanium and Zirconia Dental Implants.

Jefferson David Melo de Matos, Guilherme da Rocha Scalzer Lopes, Nathália de Carvalho Ramos, Mário Alexandre Coelho Sinhoreti, Alexandre Luiz Souto Borges, Daher Antonio Queiroz, Marco Antonio Bottino

Abstract readReview
In one paragraph

Review in Journal of clinical and experimental dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jefferson David Melo de MatosPhD, Department of Biomaterials, Dental Materials and Prosthodontics, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Sao Paulo, Brazil.
Guilherme da Rocha Scalzer LopesPhD, Department of Biomaterials, Dental Materials and Prosthodontics, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Sao Paulo, Brazil.
Nathália de Carvalho RamosAssistant Professor, Dental Materials and Prosthodontics, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Sao Paulo, Brazil.
Mário Alexandre Coelho SinhoretiFull professor, Department of Restorative Dentistry, Dental Materials Division, Piracicaba Dental School (FOP UNICAMP), Piracicaba, Sao Paulo, Brazil.
Alexandre Luiz Souto BorgesAssociate Professor, Dental Materials and Prosthodontics, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Sao Paulo, Brazil.
Daher Antonio QueirozDDS, MSc, PhD Associate Professor, Department of Restorative Sciences and Public Health Dentistry, Nova Southeastern University College of Dental Medicine, Fort Lauderdale, Florida, USA.
Marco Antonio BottinoFull professor, Department of Biomaterials, Dental Materials and Prosthodontics, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Sao Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Titanium implants are considered the gold standard for oral rehabilitation; however, zirconia implants have emerged as a metal-free alternative with promising esthetic and biological properties. Despite these advantages, limited evidence is available regarding their long-term fatigue behavior and fracture resistance. Material and Methods: In this in vitro experimental study conducted at São Paulo State University (UNESP), Brazil, forty implants were divided into two groups (n = 20): zirconia implants (ZZ) and titanium implants (TZ) (4.1 × 10 mm). Implants were embedded in polyurethane blocks according to ISO 14801:2016 specifications. Monolithic zirconia crowns were fabricated using CAD/CAM technology and cemented onto zirconia abutments. All assemblies underwent thermomechanical aging (2×106 cycles, 200 N, 2 Hz). Fatigue resistance was assessed using a stepwise loading protocol. Crown-abutment misfit was measured microscopically, and torque loss after fatigue was recorded. Statistical analysis was performed using Mann-Whitney U tests and Kaplan-Meier survival analysis ( = 0.05). Results: Zirconia implants showed significantly greater fracture resistance (1123.73 ± 153.61 N) than titanium implants (818.67 ± 42.41 N) (p = 0.037). No significant difference in fatigue survival was observed between groups (p = 0.097). The zirconia group presented greater crown-abutment misfit (39.63 ± 10.1 m) than the titanium group (25.09 ± 4.6 m) (p < 0.001). Catastrophic implant body fractures were more frequent in the zirconia group, whereas titanium implants exhibited more repairable failure modes. Conclusions: Zirconia implants demonstrated similar fracture resistance but showed catastrophic implant fractures, whereas titanium implants presented repairable failure patterns.

Identifiers

PMID42434209
PMCPMC13354055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.