ArticleNeurosurgery practice2026
Middle Fossa Craniotomy With Hydroxyapatite Cement as a Structural Repair for Noniatrogenic Cranial Cerebrospinal Fluid Leaks: A Case Series.
Article in Neurosurgery practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND AND
objectivesCranial cerebrospinal fluid (CSF) leaks due to tegmen defects can be repaired through transmastoid or transcranial surgical approaches with different repair substrates, including autologous grafts or nonimmunogenic cements. Here, we describe a case series of patients who underwent middle fossa craniotomy for repair of noniatrogenic cranial CSF leak with the use of hydroxyapatite (HA) bone cement.
methodsA retrospective analysis of all patients who underwent craniotomy with HA cement for repair of noniatrogenic cranial CSF leak at Henry Ford Hospital in Detroit between January 1, 2013, and September 30, 2024. Patient demographic features, presenting symptoms, location of cranial defect, comorbid conditions, and the outcomes of hospital length-of-stay and leak recurrence within 3-6 month follow-up were collected.
resultsHA cement middle fossa craniotomy repair of noniatrogenic cranial CSF leak was performed in 15 patients (11 women [73%] and 4 men [27%]). The median age was 56 years (range, 29-77), and the mean body mass index was 35.7 ± 8.8 kg/m
conclusionUsing HA bone cement for middle fossa craniotomy to repair cranial CSF leaks due to tegmen defects led to durable repair with no leak recurrence, suggesting that this approach may be highly effective for temporal bone repair.
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