ArticlePlastic and reconstructive surgery. Global open2026
Latissimus Dorsi Flap for Radiation-induced Chest Wall Ulcers.
Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
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Abstract
An 82-year-old female patient had a history of left breast carcinoma treated 15 years earlier with mastectomy followed by adjuvant radiotherapy. Fourteen years after the initial surgery, approximately 1 year before hospital admission, she developed a nonhealing ulcer over the left anterior chest wall at the site of prior irradiation. The patient has a history of hypertension, kidney failure, and malnutrition. The patient underwent biopsy, which excluded recurrent malignancy, and subsequently received outpatient wound care. Despite more than 8 months of wound management, the lesion progressively enlarged and eventually exposed the fifth rib. The patient underwent multidisciplinary consultation, and a decision was made to optimize general condition, manage underlying medical comorbidities, and perform wide excision of fibrotic and indurated tissue, followed by reconstruction of the defect using a pedicled latissimus dorsi musculocutaneous flap. The wound healed within 2 weeks. At the 5-month follow-up, the wound demonstrated satisfactory healing with no complications observed. This case suggests that radiation-induced wounds are classified as chronic nonhealing wounds, primarily due to radiation-associated fibrosis and compromised vascularity within the irradiated field. Definitive management requires wide excision of fibrotic, poorly perfused tissue, followed by reconstruction with well-vascularized tissue. In our case, persistence of ulceration for more than 8 months was excessively prolonged. Early multidisciplinary collaboration (including oncology, plastic and reconstructive surgery, and wound care specialists) would have facilitated earlier surgical intervention.
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