ArticleFrontiers in neurology
Endolymphatic hydrops in patients with migraine: a correlative study.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Endolymphatic hydrops (EH), Menière's disease (MD) pathological hallmark, is visualized via 3 T delayed phase MRI. This study examines MRI correlations between EH severity and migraine brain biomarkers. Methods: Retrospective review of 144 inner ear MRI scans yielded 108 patients with confirmed EH. Two blinded radiologists graded EH, assessed migraine markers (white matter lesions (WML), frontal predominance of WML, enlarged perivascular spaces), and measured cranial nerve volumes. Binary logistic regression tested associations. Results: Mean age 53.6 ± 15.8 years (56.5% female). Grade 2 vestibular EH predominated bilaterally; grade 2 cochlear EH affected 34-43%. No EH associations with migraine biomarkers or cranial nerve volumes were found (all Conclusion: EH severity was not associated with established migraine MRI biomarkers in this cohort. These findings support the concept that EH and migraine-related structural brain changes may represent distinct imaging phenomena.
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