Evidence map›Paper›PMID 42433935›Full record

ArticleTranslational pediatrics2026

Routine admission biomarkers for identifying co-infection and stratifying severity in pediatric macrolide-resistant

Xiaofei Bi, Kuo Wang, Huan Meng, Shuxiao Qiu, Yujia Tang, Yilu Lin, Di Wu, Huiying Liu, Xiaohui Jiang, Yuanyuan Ji and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiaofei Bi *Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, China.
Kuo Wang *Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Huan Meng *Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, China.
Shuxiao Qiu *Department of Emergency, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Yujia TangDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, China.
Yilu LinDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, China.
Di WuDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, China.
Huiying LiuDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, China.
Xiaohui JiangDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, China.
Yuanyuan JiDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Jianing ZhangDepartment of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Bowen LiuDepartment of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Kai KangDepartment of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yan GaoDepartment of Critical Care Medicine, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Yang GaoDepartment of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early identification of co-infection and timely risk stratification remain difficult in children with pneumonia caused by macrolide-resistant Methods: This single-center retrospective cohort study included children with MRMP pneumonia admitted to The Sixth Affiliated Hospital of Harbin Medical University from August 1 to December 31, 2023. MRMP was confirmed by targeted next-generation sequencing (t-NGS) detection of Results: A total of 278 children with MRMP pneumonia were enrolled, including 78 with mono-infection and 200 with co-infection. In the first-stage analysis, platelet (PLT) levels on admission were higher in the co-infection group than in the mono-infection group [290.50 (243.00, 362.00) Conclusions: In children with MRMP pneumonia, PLT showed limited discriminatory value for identifying bacterial and/or viral co-infection, whereas lower ALB and higher PCT on admission were associated with severe disease among co-infected children.

Indexed as

albumin (ALB)co-infectionMacrolide-resistant Mycoplasma pneumoniae pneumonia (MRMP pneumonia)platelet (PLT)procalcitonin (PCT)

Identifiers

PMID42433935
PMCPMC13351663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.