Evidence map›Paper›PMID 42433735›Full record

ArticleUrology case reports2026

Prenatal sex discordance revealing SRY-positive 46,XX testicular disorder of sex development.

Sebastian Tobia-Gonzalez, Natalie Barganski, Melissa Miller, Alicia Renck, Leon Smith-Harrison

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebastian Tobia-GonzalezDivision of Pediatric Urology, Driscoll Children's Hospital, Corpus Christi, TX, USA.
Natalie BarganskiDivision of Pediatric Urology, Driscoll Children's Hospital, Corpus Christi, TX, USA.
Melissa MillerDivision of Pediatric Urology, Driscoll Children's Hospital, Corpus Christi, TX, USA.
Alicia RenckDivision of Pediatric Genetics, Driscoll Children's Hospital, Corpus Christi, TX, USA.
Leon Smith-HarrisonDivision of Pediatric Urology, Driscoll Children's Hospital, Corpus Christi, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

46,XX testicular disorder of sex development (DSD) is a rare condition usually diagnosed during adolescence or adulthood due to infertility or hypogonadism. Early diagnosis in phenotypically normal infants is uncommon. We report a male infant identified following discordant prenatal sex assessment, with noninvasive prenatal testing suggesting a female fetus and prenatal ultrasonography demonstrating male genitalia. Postnatal chromosomal analysis revealed 46,X,add(X) (p22.3) with SRY positivity. Physical examination showed normal male external genitalia with bilaterally descended testes and no genital anomalies. After two years of multidisciplinary follow-up, the patient remained clinically stable without gonadal abnormalities.

Indexed as

46,XX testicular disorder of sex developmentDe la Chapelle syndromePrenatal sex discordanceSRY-Positive XX male

Identifiers

PMID42433735
PMCPMC13351684

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.