Evidence map›Paper›PMID 42433726›Full record

ArticleRadiology case reports2026

Bone marrow predominant presentation of EGFR mutated NSCLC: Report of two cases.

Sayed M S Hashemi, Denise W M de Jong, Josephine Mathilde Iris Vos, Emile Comans, Idris Bahce

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sayed M S HashemiDepartment of Pulmonary Medicine, Amsterdam Cancer Center, Amsterdam University Medical Center, location VU University Medical Center, Amsterdam, The Netherlands.
Denise W M de JongDepartment of Pulmonary Medicine, Haaglanden Medisch Centrum, Location Antoniushove, Leidschendam, The Netherlands.
Josephine Mathilde Iris VosDepartment of Hematology, Amsterdam University Medical Center, Location University of Amsterdam, Amsterdam, The Netherlands.
Emile ComansDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Location VU University Medical Center, Amsterdam, The Netherlands.
Idris BahceDepartment of Pulmonary Medicine, Amsterdam Cancer Center, Amsterdam University Medical Center, location VU University Medical Center, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Epidermal Growth Factor Receptor (EGFR) mutations are present in a minority of cases of non-small cell lung cancer (NSCLC), most commonly among never-smokers. In metastatic EGFR-positive NSCLC the most frequently involved sites are the bone and brain, a miliary metastatic subset also exists. However, cases with predominant bone marrow involvement have not been previously described. Here, we present two cases characterized by bone marrow predominance as an unusual initial imaging finding, with the diagnosis confirmed by bone marrow biopsy. Treatment was successful, comparable to usual EGFR-positive cases.

Indexed as

Bone marrowEGFRNSCLC

Identifiers

PMID42433726
PMCPMC13352072

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.