ArticleFrontiers in public health2026
Association of radiation exposure and blood lipid derived indices with hypertension risk in radiation workers.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study aimed to explore the relationships between occupational radiation exposure, serum lipid levels and hypertension, and to assess the potential intermediate role of lipid parameters in the relevant association. Methods: A cross-sectional study (2,548 subjects) and a retrospective cohort study (484 subjects) were conducted among radiation workers who underwent physical examinations at a medical center in Shijiazhuang from October 2021 to March 2025. In the cross-sectional study, multivariate Logistic regression, restricted cubic spline (RCS) and mediation analysis were used to explore the association between radiation exposure and hypertension, as well as the mediating role of lipid parameters. In the cohort study, Cox proportional hazards regression, Kaplan-Meier curve, receiver operating characteristic (ROC) curve, stratified analysis and sensitivity analysis were applied to evaluate the association and predictive performance of baseline lipid indices for incident hypertension. Results: The cross-sectional analysis showed that, after adjustment for confounders, radiation working years, high working-year group and industrial radiation exposure were risk factors for hypertension (all Conclusion: Prolonged radiation working years and industrial radiation exposure are associated with an increased risk of hypertension in radiation workers, and lipid profiles may play a mediating role. FBG/HDL-C, TC/HDL-C and NHHR are superior to conventional lipid indices in predicting hypertension. Male and overweight radiation workers are key targets for hypertension prevention and control.
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