Evidence map›Paper›PMID 42432833›Full record

ReviewCancer medicine2026

Watch and Wait Strategy for Locally Advanced Rectal Cancer: Update From Results of Recent Clinical Trials.

Ruocheng Yin, Zhigang Chen, Xinliang Liu, Dan Zong, Xia He

Abstract readReview
In one paragraph

Review in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruocheng YinXuzhou Medical University, Xuzhou, Jiangsu, China.ORCID https://orcid.org/0009-0000-2029-7321
Zhigang ChenDepartment of Gastrointestinal Surgery, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, The Third Affiliated Hospital of Nanjing Medical University, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China.
Xinliang LiuDepartment of Radiotherapy, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, and Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, China.
Dan ZongDepartment of Radiotherapy, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, and Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0001-7927-5215
Xia HeXuzhou Medical University, Xuzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-7314-1002

Funding

Yishan Research Project of Jiangsu Cancer Hospital YSZD202402
6 · The paper itself

Abstract

Locally advanced rectal cancer (LARC) is a common malignant tumor in the digestive system. Currently, despite growing recognition of personalized medicine, systematic risk stratification and full incorporation of patient preferences for anal preservation and treatment tolerance remain challenging in some clinical settings. This review summarizes the latest clinical research progress on the watch-and-wait (W&W) strategy for LARC, including the applicable population of W&W, the factors predicting tumor regression, and the methods to increase the W&W rate. By synthesizing the current evidence, this review aims to inform clinical decision-making and advance the practice of evidence-based precision medicine.

Indexed as

Rectal NeoplasmsWatchful WaitingClinical Trials as TopicHumansNeoadjuvant TherapyNeoplasm Stagingimmunotherapylocally advanced rectal cancerneoadjuvant chemoradiotherapytotal neoadjuvant therapywatch and wait

Identifiers

PMID42432833
PMCPMC13354755

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.