ArticleBMC psychology2026
Determinants of kinesiophobia in patients with hidradenitis suppurativa: the role of pain, fatigue, physical activity and depression.
Article in BMC psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with substantial physical and psychosocial burden. Pain, fatigue, and psychological symptoms are common in HS and may influence behavioral responses such as fear of movement. Kinesiophobia, defined as an excessive fear of movement due to pain or fear of injury, has been widely studied in chronic pain conditions; however, its role in HS has not been previously investigated. This study aimed to evaluate the level of kinesiophobia in patients with HS and to investigate its associations with disease severity, pain, fatigue, psychological symptoms, and physical activity.
methodsThis cross-sectional study included patients with HS and age- and sex-matched healthy controls. Disease severity was assessed using the International Hidradenitis Suppurativa Severity Score System (IHS4). Pain intensity was evaluated using the Visual Analog Scale (VAS), fatigue using the Fatigue Severity Scale (FSS), depressive symptoms using the Beck Depression Inventory (BDI), anxiety using the Beck Anxiety Inventory (BAI), physical activity using the MET scale, and kinesiophobia using the Tampa Scale for Kinesiophobia (TSK). Group comparisons, correlation analyses, and multivariable regression analysis were performed to identify factors independently associated with kinesiophobia.
resultsPatients with HS had significantly higher levels of kinesiophobia and fatigue and lower levels of physical activity compared with healthy controls. Kinesiophobia was positively correlated with disease severity, pain intensity, fatigue, and depressive symptoms, and negatively correlated with physical activity levels. In multivariable regression analysis, pain intensity, fatigue, and depressive symptoms emerged as independent determinants of kinesiophobia.
conclusionsKinesiophobia appears to be an important yet underrecognized component of disease burden in HS. Pain, fatigue, and depressive symptoms may contribute to the development of movement-related fear, which may in turn reduce physical activity levels. Multidisciplinary management strategies addressing pain control, fatigue, psychological well-being, and safe physical activity may help improve patient outcomes in HS.
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