Evidence map›Paper›PMID 42432752›Full record

ArticleBMC chemistry2026

Regioselective electrosynthesis of pyrazolo[3,4-b]quinolin-5-one derivatives.

Eman O Osman, Amr M Mahmoud, Hala B El-Nassan

Abstract read
In one paragraph

Article in BMC chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eman O OsmanPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Amr M MahmoudAnalytical Chemistry Department, Faculty of Pharmacy, Cairo University, 33 Kasr El-Aini Street, Cairo, 11562, Egypt.
Hala B El-NassanPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. hala.el-nassan@pharma.cu.edu.eg.

Funding

Science and Technology Development Fund 45569
6 · The paper itself

Abstract

A highly efficient and regioselective method had been reported for the synthesis of pyrazoloquinoline derivatives. The current work studied the reaction of 3-indolylpyrazole, dimedone, and various aldehydes under electrochemical conditions. The various factors controlling electrochemical reactions were examined and optimized, including reaction time, temperature, current, solvent, type of electrodes, and supporting electrolytes. The scope of the reaction was investigated using different types of aldehydes. The reaction yielded exclusively pyrazolo[3,4-b]quinolin-5-ones in high yields and mild reaction conditions. The structure of the products was confirmed by

Indexed as

Electrochemical synthesisGreen chemistryPyrazoloquinolineRegioselective

Identifiers

PMID42432752
PMCPMC13355326

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.