Evidence map›Paper›PMID 42432732›Full record

ArticleBioData mining2026

A three-level risk stratification algorithm for arrhythmia based on CNN-LSTM palindromic structure.

Hua Zhang, Jing Li, Mingjie Wang, Xuexi Xuan, Kai Xia, Yuanyuan Tan, Li Li, Jianfeng Chen, Haiyan Wang

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Article in BioData mining, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Hua ZhangDepartment of Cardiology, Zhengzhou Seventh People's Hospital, Zhengzhou, 450000, China.
Jing LiDepartment of Cardiology, Zhengzhou Seventh People's Hospital, Zhengzhou, 450000, China. lijing201912@126.com.ORCID http://orcid.org/0009-0006-5633-7333
Mingjie WangDepartment of Cardiology, Zhengzhou Seventh People's Hospital, Zhengzhou, 450000, China.
Xuexi XuanDepartment of Cardiology, Zhengzhou Seventh People's Hospital, Zhengzhou, 450000, China.
Kai XiaDepartment of Cardiology, Zhengzhou Seventh People's Hospital, Zhengzhou, 450000, China.
Yuanyuan TanDepartment of Cardiology, Zhengzhou Seventh People's Hospital, Zhengzhou, 450000, China.
Li LiDepartment of Cardiology, Zhengzhou Seventh People's Hospital, Zhengzhou, 450000, China.
Jianfeng ChenSchool of Computer Science, Zhengzhou University of Aeronautics, Zhengzhou, 450046, China.
Haiyan WangSchool of Computer Science, Zhengzhou University of Aeronautics, Zhengzhou, 450046, China.

Funding

Guidance Plan Project for Technological Innovation in Zhengzhou's Medical and Health Field 2024YLZDJH224Key Research Project Support Program for Higher Education Institutions in Henan Province 25A520010National Natural Science Foundation of China 62302463
6 · The paper itself

Abstract

Cardiovascular diseases are characterized by sudden onset, high mortality rates, and high recurrence rates, making early screening and timely intervention essential. However, due to insufficient medical resources, real-time and refined electrocardiogram monitoring of patients is difficult to implement. Meanwhile, the complex spatiotemporal features of electrocardiogram (ECG) signals bring challenges to multidimensional feature mining and accurate recognition. Therefore, in this study, we propose a three-level risk stratification algorithm for arrhythmia, which not only ensures precise intervention for different types of arrhythmias to achieve optimized allocation of medical resources but also comprehensively captures the spatiotemporal features of ECG signals for high-accuracy risk stratification detection. The algorithm first proposes a three-level arrhythmia risk stratification scheme, classifying cases as Normal, Not Life-threatening, and Life-threatening, with corresponding intervention measures of no need for monitoring, close attention, and immediate intervention, respectively. The core model of this algorithm is a deep learning fusion network based on the palindromic structure of Convolutional Neural Network (CNN) and Long Short-Term Memory network (LSTM), which enables precise three-level risk detection for all types of arrhythmias. Experimental results demonstrate that the algorithm exhibits favorable generalization performance across multiple datasets. It not only outperforms standalone CNN and LSTM models but also surpasses classical classifiers. Notably, on the 2-second ECG segments from the gold-standard dataset, it achieves an accuracy of 99.68% and a Specificity of 99.65%.The 10-fold cross-validation yields an accuracy of 99.62% ± 0.09% for 3-second segments, and patient-level validation on 10-second segments achieves an accuracy of 96.5%. The satisfactory results across varied segment lengths verify the reliability and practicality of the proposed method. In both arrhythmia risk stratification and detection tasks, the algorithm presents moderate competitive advantages.

Indexed as

Arrhythmias risk detectionConvolutional Neural NetworkLong Short-Term Memory networkPalindromic structureRisk stratification algorithm

Identifiers

PMID42432732
PMCPMC13640309

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