ArticleMicrobial cell factories2026
Development and optimization of a glycerol-based fed-batch strategy for the production of peroxidases with Komagataella phaffii under the P
Article in Microbial cell factories, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Thinking big in small scale: characterization of peroxidase production in Komagataella phaffii using two-compartment scale-down system.Bioprocess and biosystems engineering · 2026Article
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8 authors.
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Abstract
backgroundUnsaturated polyester resins are commonly polymerized using cobalt-based siccatives. However, growing health concerns and increasing demand for cobalt highlight the need for more sustainable alternatives. Heterologously produced peroxidases, produced through secretory expression in Komagataella phaffii (K. phaffii, previously classified as Pichi a pastoris), represent a promising substitute for cobalt in such applications. To tailor the bioprocess for the production of peroxidases, dedicated bioprocess development and optimization are required. Rather than relying on methanol induction, the process should aim to achieve production via glycerol derepression under the control of the P
resultsThis study presents the development and optimization of a three-phase bioprocess for peroxidase production in K. phaffii under the P
conclusionsThis work demonstrates the feasibility of a robust, methanol-free bioprocess for peroxidase production in K. phaffii, driven by glycerol derepression under the P
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