Evidence map›Paper›PMID 42432643›Full record

ArticleBMC palliative care2026

Promoting palliative care for people with heart failure: the P3HF study protocol.

Yutong Men, Nathan Wright, Giselle O'Connor, Ling Han, Hargun Kaur, Ella Suh, Jenny Chen, Bashar Kadhim, Tariq Ahmad, Michael Beasley and 5 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC palliative care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06933875 (Promoting Palliative Care for People With Heart Failure), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06933875 narecruitingnot on this map

Promoting Palliative Care for People With Heart Failure: The P3HF Pilot Study

TypeinterventionalSponsorYale UniversityRan2026 to 2027Enrolled2,260ConditionsHeart Failure, Palliative CareArmsClinical Decision Support Tool
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yutong MenYale School of Public Health, 60 College St, New Haven, CT, 06510, USA. yutong.men@yale.edu.
Nathan WrightYale School of Nursing, 400 West Campus Drive, Orange, CT, 06477, USA.
Giselle O'ConnorYale School of Nursing, 400 West Campus Drive, Orange, CT, 06477, USA.
Ling HanYale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Hargun KaurYale School of Nursing, 400 West Campus Drive, Orange, CT, 06477, USA.
Ella SuhYale School of Public Health, 60 College St, New Haven, CT, 06510, USA.
Jenny ChenYale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Bashar KadhimYale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Tariq AhmadYale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Michael BeasleyYale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Nora SegarYale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Nancy KimYale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Jonathan QuangYale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.
Mona SharifiYale School of Public Health, 60 College St, New Haven, CT, 06510, USA.
Shelli FederYale School of Nursing, 400 West Campus Drive, Orange, CT, 06477, USA.

Funding

Promoting Palliative Care for People with Heart Failure: The P3HF Pilot StudyR34HL174885 · NHLBI · YALE UNIVERSITY · PI Shelli Leore Feder · 2024 to 2026
$719k
National Heart, Lung, and Blood Institute (NHLBI) R34HL174885NHLBI NIH HHS R34 HL174885
6 · The paper itself

Abstract

backgroundHeart failure is often a chronic, life-limiting illness associated with high symptom burden, frequent hospitalizations, and substantial suffering near the end of life. Although palliative care improves quality of life and is strongly recommended by clinical practice guidelines, fewer than 20% of people with heart failure receive it. We developed the Promoting Palliative Care for People with Heart Failure (P3HF) Clinical Decision Support (CDS) tool-an evidence-based, end-user informed tool integrating a validated prognostic-risk model, tiered functionality, and behavioral nudges in the electronic health record (EHR). This manuscript describes the development of the P3HF CDS and protocol for a clinical trial evaluating its effects.

methodsWe will conduct a pragmatic randomized clinical trial at two large urban hospitals, within a single health system, using an embedded, convergent mixed-methods design to evaluate the P3HF CDS. Eligible patients are adults (≥ 18 years) hospitalized with heart failure, N-terminal pro-B-type natriuretic peptide (NT-proBNP) ≥ 500 pg/mL, and receipt of intravenous diuretics within 24 h of admission. We will analyze data from the EHR and surveys and interviews with end-users (attending physicians, residents, fellows, advanced practice providers) of the CDS tool and palliative care clinicians to assess CDS usability, acceptability, appropriateness, feasibility (implementation outcomes), and efficacy in increasing inpatient palliative care (Primary clinical outcome) consultations. Secondary exploratory outcomes include increasing palliative care outpatient referrals, improved advance care planning documentation, higher hospice enrollment, and reductions in hospital length of stay and 30-day readmissions compared to usual care. DISCUSSION: The P3HF CDS is an evidence-based, theory and end-user informed tool designed to promote timely palliative care for people with heart failure. The P3HF trial will examine the acceptability and effects of the CDS in real-world clinical settings.

trial registrationNCT06933875 ( https://clinicaltrials.gov/study/NCT06933875 , Registration date: 2025-04-18).

Indexed as

Heart FailurePalliative CareDecision Support Systems, ClinicalHumansPragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicClinical decision support toolHeart failurePalliative care

Identifiers

PMID42432643
PMCPMC13640078

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.