Evidence map›Paper›PMID 42432569›Full record

ArticleBMC ophthalmology2026

Dynamic changes in axial length and refractive error following intraocular pressure normalization in acute primary angle-closure glaucoma.

Yin Zhang, Qi Chen, Yue Wang, Qingmin Ma, Juan Li, Jianmin Wang, Fang Fan

Abstract read
In one paragraph

Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yin Zhang *Hebei General Hospital, No.348 West Heping Road, Xinhua District, Shijiazhuang City, Hebei Province, China.
Qi Chen *Hebei General Hospital, No.348 West Heping Road, Xinhua District, Shijiazhuang City, Hebei Province, China.
Yue WangHebei General Hospital, No.348 West Heping Road, Xinhua District, Shijiazhuang City, Hebei Province, China.
Qingmin MaHebei General Hospital, No.348 West Heping Road, Xinhua District, Shijiazhuang City, Hebei Province, China.
Juan LiHebei General Hospital, No.348 West Heping Road, Xinhua District, Shijiazhuang City, Hebei Province, China.
Jianmin WangHebei General Hospital, No.348 West Heping Road, Xinhua District, Shijiazhuang City, Hebei Province, China.
Fang FanHebei General Hospital, No.348 West Heping Road, Xinhua District, Shijiazhuang City, Hebei Province, China. fanfang2004@sina.com.

Funding

Hebei Provincial Medical Science Research Project No.20220830S&T Program of Hebei No.18277753D
6 · The paper itself

Abstract

purposeTo investigate the dynamic changes in axial length (AL) and refractive error following the normalization of intraocular pressure (IOP) in acute primary angle-closure glaucoma (APACG).

methodsThis study included thirty-one consecutive patients with APACG. AL and keratometric values were measured using IOLMaster before IOP normalization, after IOP normalization, and postoperatively. The analysis focused on IOP levels, AL, keratometric values, and the anticipated refractive discrepancy (the expected refractive error post-IOP normalization with intraocular lens power for emmetropia correction predetermined pre-IOP normalization).

resultsAfter IOP normalization, AL decreased significantly from 22.7 to 22.4 mm and IOP from 57.5 to 16.5 mmHg (P < 0.001). The change in IOP was positively correlated with the change in AL (r = 0.451, P = 0.011), with a decrease of 0.05 mm in AL per 10-mmHg reduction in IOP (P = 0.011). Moreover, the alteration in IOP was associated with the predicted refractive difference (r = 0.431, P = 0.015) and a predicted refractive difference of + 0.26 diopter (D) per 10-mmHg decrease in IOP (P = 0.015).

conclusionsDecreased IOP correlated with reduced AL and increased predicted refractive error (hyperopia). Therefore, lowering IOP before biometric assessment may improve refractive outcomes when feasible. In cases requiring immediate intervention, each 1-mmHg reduction in IOP decreases AL by 5 μm, yielding a hyperopic shift of 0.026 D.

Indexed as

Axial Length, EyeGlaucoma, Angle-ClosureIntraocular PressureRefractive ErrorsAcute DiseaseAgedFemaleHumansMaleMiddle AgedRefraction, OcularTonometry, OcularAcute primary angle-closure glaucomaAxial lengthIntraocular pressurePredicted refractive difference

Identifiers

PMID42432569
PMCPMC13644223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.