Evidence map›Paper›PMID 42432559›Full record

ArticleBMC public health2026

Socioeconomic status and cognitive function in older adults: the mediating roles of social activity and loneliness in three aging cohorts.

Rui Dong, Lin Gui, Dexiang Xu, Huijuan Li

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Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Rui DongDepartment of Respiratory and Critical Care Medicine, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, Shandong, China.
Lin GuiDepartment of Geriatrics, Liyuan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.
Dexiang XuDepartment of Respiratory and Critical Care Medicine, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, Shandong, China.
Huijuan LiShibei District Maternal and Child Health and Family Planning Service Center, Qingdao, Shandong, China. lihuijuan311@163.com.

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6 · The paper itself

Abstract

backgroundCognitive impairment among older adults poses a substantial and growing public health burden. Despite established links between SES and cognition, the psychosocial pathways and their variation across national contexts remain unclear. This study examines the relationship between SES and cognitive function in middle-aged and older adults, and explores the mediating roles of social activity and loneliness in this association.

methodsUsing data from the China Health and Retirement Longitudinal Study (CHARLS), the Health and Retirement Study (HRS) in the United States and the English Longitudinal Study of Ageing (ELSA), we analyzed participants aged ≥ 50. SES was derived from latent class analysis of family income, educational level, and employment status. Cognitive function was assessed through standardized tests. Linear mixed models evaluated SES-cognition associations, and mediation analyses explored potential associative pathways.

resultsHigher SES was significantly associated with better cognitive function in all cohort studies, with the strength of the association varying cross-nationally: strongest in CHARLS (β = 0.21, 95% CI: 0.16-0.26), intermediate in HRS (β = 0.14, 0.11-0.17), and weakest in ELSA (β = 0.031, 0.003-0.058). Social activities mediated 7.28% to 12.08%, and loneliness mediated 1.89% to 18.33% of these associations. The relationships remained consistent across the subgroups.

conclusionSocioeconomic status demonstrated a robust, graded association with cognitive function in older adults, with this relationship partially mediated by social activity involvement and loneliness. The cross-national gradient in effect sizes suggests that macro-level structural and policy contexts may substantially moderate this relationship. These findings highlight the need for integrated interventions addressing both psychosocial mediators and structural determinants to reduce cognitive health disparities.

Indexed as

AgingCognitionLonelinessSocial ClassSocial ParticipationAgedAged, 80 and overChinaCohort StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedSocioeconomic Disparities in HealthUnited StatesCognitive functionCohort studiesLonelinessSocial activitySocioeconomic status

Identifiers

PMID42432559
PMCPMC13602647

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.