Trial reportAesthetic plastic surgery2026
Intradermal Injections of 10% Glucose (Sihler G) for Scalp Hair Regrowth: A Randomized, Evaluator-Blinded Pilot Study.
Trial report in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAndrogenetic alopecia (AGA) is a common non-scarring alopecia with substantial psychosocial burden. Minoxidil and 5α-reductase inhibitors remain standards of care but require prolonged adherence and do not fully address the dermal microenvironment.
objectiveTo evaluate efficacy and safety of intradermal 10% glucose combined with non-cross-linked hyaluronic acid (NHA) versus NHA alone for scalp hair regrowth.
methodsIn this prospective, single-center, randomized, evaluator-blinded pilot study, 40 adults with mild-to-moderate AGA (Norwood-Hamilton II-IV or Ludwig I-II) were randomized 1:1 to receive intradermal 10% glucose + NHA (Sihler G, Sihler Inc., Korea) or NHA alone. Participants underwent five sessions at 3-week intervals (weeks 0-12). This pilot study was not prospectively registered. The primary end point was change in terminal hair density (hairs/cm
resultsThirty-eight participants completed the study (19 per group). At week 18, mean terminal hair density increased by + 19.3 ± 8.1 hairs/cm
conclusionIn this pilot RCT, intradermal 10% glucose combined with NHA produced greater improvements in objective and subjective hair outcomes than NHA alone, with a favorable shortterm safety profile. Larger, longer trials are warranted. LEVEL OF EVIDENCE II: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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