Evidence map›Paper›PMID 42432331›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Matched case-control study of odontoid osteosynthesis vs hard collar immobilisation for Type II odontoid fractures in the elderly: higher risk of adverse events with no long-term functional benefits.

Laura Martou, Jigyasa Madan, Surya Batas, Santhosh G Thavarajasingam, Jin-Sung Kim, Darren F Liu, Salvatore Russo

Abstract readComparative Study
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Laura MartouImperial College London, London, UK. lauramartou@gmail.com.ORCID https://orcid.org/0000-0001-8872-0085
Jigyasa MadanImperial College London, London, UK.
Surya BatasSeoul St. Mary's Hospital, Seoul, Korea, Republic of.
Santhosh G ThavarajasingamLMU Klinikum, Munich, Germany.
Jin-Sung KimSeoul St. Mary's Hospital, Seoul, Korea, Republic of.
Darren F LiuMater Private Hospital, Dublin, Ireland.
Salvatore RussoImperial College Healthcare NHS Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOdontoid fractures in the elderly carry high morbidity and mortality, yet optimal management remains controversial. This study compares functional and radiological outcomes between anterior odontoid screw fixation (AOSF) and hard collar immobilisation in elderly patients with acute Type II odontoid fractures.

methodsSingle-centre matched case-control study of AOSF versus hard collar immobilisation in patients ≥ 65 years. Patients were matched using clinical outcome predictors (age; frailty; co-morbidities; fracture morphology). Included patients were deemed by the lead surgeon and multidisciplinary team to have sufficient clinical equipoise between operative and non-operative management. Outcomes were collected retrospectively (complications, mortality, union rates, screw positioning) and prospectively using patient-reported outcome measures (Visual Analogue Scale [VAS]; Neck Disability Index [NDI]; EQ-5D-5 L; Dysphagia Outcome and Severity Scale [DOSS]).

resultsOf 381 acute odontoid fractures, 70 met the inclusion criteria (35 AOSF; 35 matched Hard Collar). The operative group had longer hospitalisation (21 ± 23.69 vs. 11 ± 7.52 days; p = 0.042) and higher incidence of adverse events per patient (2.17 vs. 0.91, p < 0.001). Dysphagia occurred in 46% of operative cases. Seven screw-related complications occurred, with one revision. Three treatment-related deaths occurred in the operative group; none in the conservative. Functional outcomes were similar between groups; however, neck pain (VAS) was lower following AOSF (2.00 ± 2.02 vs. 4.69 ± 3.95; p = 0.008). Non-union rates were comparable.

conclusionsOdontoid osteosynthesis was associated with longer hospitalisation, treatment-related morbidity and mortality, while demonstrating a marginal improvement in neck pain. Larger randomised studies are needed to determine the role of AOSF in this population.

Indexed as

Fracture Fixation, InternalImmobilizationOdontoid ProcessSpinal FracturesAgedAged, 80 and overBone ScrewsCase-Control StudiesFemaleHumansMaleRetrospective StudiesTreatment OutcomeAnterior screw fixationConservative managementElderlyMorbidityMortalityOdontoid fracture

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.