Evidence map›Paper›PMID 42432323›Full record

ReviewBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2026

Recent advances in therapeutic agents for uranium poisoning: a comprehensive review.

Juan Li, Wenrun Li, Feng Huang, Qiuchi Wang, Hongjia Liu, Liyi Chen, Qiuping Wang, Yong Li, Shiyan Fu, Yazhen Zhao and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juan LiState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Wenrun LiState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Feng HuangState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Qiuchi WangState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Hongjia LiuState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Liyi ChenState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Qiuping WangState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Yong LiState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Shiyan FuState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Yazhen ZhaoState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China.
Yonghong RanState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. 1048765288@qq.com.
Yuhui HaoState Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. yuhuihao@tmmu.edu.cn.ORCID https://orcid.org/0000-0002-7161-2624

Funding

National Natural Science Foundation of China 82473576]Technology Research Program of Chongqing Municipal Education Commission KJQN202412806
6 · The paper itself

Abstract

Uranium-an emerging pollutant that exhibits both radioactivity and heavy metal toxicity-is extensively used in nuclear fuel and military applications. Occupational and environmental exposure during its extraction, production, and utilization poses significant health risks. Consequently, developing effective countermeasures against uranium poisoning remains a critical challenge in the field of medical research. This review systematically introduces the latest experimental progress in research on drugs for treating uranium toxicity. It specifically elucidates the mechanisms and efficacy evaluations of multiple detoxification strategies, including chelating agents, nanomedicines, biosynthetic compounds, small molecules, natural medicines, and plant extracts. By analyzing innovative drug design principles and evaluating their mechanistic effects on uranium toxicity, this work provides critical insights for the future development of highly effective and low-toxicity novel therapies for uranium poisoning.

Indexed as

Chelating AgentsPoisoningUraniumAnimalsHumansPlant ExtractsChelating AgentsPlant ExtractsUraniumDecorporation agentsNatural medicineSmall moleculesTreatmentUranium poisoning

Identifiers

PMID42432323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.