Evidence map›Paper›PMID 42432310›Full record

ArticleProbiotics and antimicrobial proteins2026

Deciphering the Anticancer Potential of Bifidobacterium longum MB BBLM15 Derived Postbiotic Metabolites in Cervical Cancer: In Vitro, In Silico, and Synergy Studies.

Adrija Mukherjee, Debraj Chakraborty, Arpita Robel Khamle, Darsh D Sharma, Hemang Patel, Umang Shah, Atanu Banerjee, Parth Sarthi Sen Gupta, Ankit Rai, Gaurav Kaushik and 3 more

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Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Adrija MukherjeeB. D. Patel Institute of Allied and Healthcare Sciences, Charotar University of Science and Technology, CHARUSAT Campus, Changa, Gujarat, 388421, India.
Debraj ChakrabortyDr. K. C. Patel Research and Development Centre, Charotar University of Science and Technology (CHARUSAT), Anand, Gujarat, India.
Arpita Robel KhamleSchool of Biosciences and Bioengineering, D Y Patil International University, Akurdi, Pune, Maharashtra, India.
Darsh D SharmaDepartment of Medical Biotechnology, Gujarat Biotechnology University, Gandhinagar, Gujarat, 382355, India.
Hemang PatelDepartment of Medical Biotechnology, Gujarat Biotechnology University, Gandhinagar, Gujarat, 382355, India.
Umang ShahRamanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT Campus, Anand, Gujarat, 388421, India.
Atanu BanerjeeDr. K. C. Patel Research and Development Centre, Charotar University of Science and Technology (CHARUSAT), Anand, Gujarat, India.
Parth Sarthi Sen GuptaSchool of Biosciences and Bioengineering, D Y Patil International University, Akurdi, Pune, Maharashtra, India.
Ankit RaiDepartment of Medical Biotechnology, Gujarat Biotechnology University, Gandhinagar, Gujarat, 382355, India.
Gaurav KaushikMeteoric Biopharmaceuticals PVT. LTD, Ahmedabad, India.
Mruduka PatelMeteoric Biopharmaceuticals PVT. LTD, Ahmedabad, India.
Gayatri PatelRamanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT Campus, Anand, Gujarat, 388421, India.
Ruma SarkarB. D. Patel Institute of Allied and Healthcare Sciences, Charotar University of Science and Technology, CHARUSAT Campus, Changa, Gujarat, 388421, India. rumasarkar.cips@charusat.ac.in.ORCID http://orcid.org/0000-0002-6450-5185

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics are beneficial microorganisms that exert several health-promoting effects, while their metabolites, referred to as postbiotics, have recently gained increasing attention for their therapeutic relevance. The present study elucidates the anticancer potential of Bifidobacterium longum MB BBLM15-derived postbiotic metabolites through an integrated experimental and computational approach. Postbiotic metabolites were extracted from Bifidobacterium longum MB BBLM15 using three different solvents (hexane, dichloromethane, ethyl acetate) and subsequently subjected to metabolic profiling. The cytotoxic potential of the three extracts was assessed against cervical cancer cells (HeLa) using a cell viability assay. Hexane-extracted postbiotic metabolites (HX-PM) showed the most potent cytotoxic activity (IC

Indexed as

Anti-cancer activitiesBifidobacterium longum MB BBLM15Cervical cancerMetabolomic profilingPostbiotic metabolitesSynergism

Identifiers

PMID42432310

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.