Evidence map›Paper›PMID 42432171›Full record

ArticleBone marrow transplantation2026

Timing is everything: outcomes of allogeneic HSCT in adults with inborn errors of immunity.

Katharine Orf, Hannah Al Yousuf, Thomas A Fox, Nadhira Samsudeen, Suzanne Elcombe, Mari Campbell, Stephen Jolles, Niall Conlon, Charu Chopra, Jennifer M Tjon and 56 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone marrow transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

66 authors.

Katharine Orf *Institute of Immunity & Transplantation, University College London, London, UK.ORCID 0000-0003-3826-5293
Hannah Al Yousuf *Department of Haematology, University College London Hospitals NHS Foundation Trust, London, UK.
Thomas A FoxInstitute of Immunity & Transplantation, University College London, London, UK.ORCID 0000-0002-1163-2295
Nadhira SamsudeenUniversity College London Medical School, London, UK.
Suzanne ElcombeNewcastle Hospitals NHS Foundation Trust, Newcastle, UK.
Mari CampbellInstitute of Immunity & Transplantation, University College London, London, UK.
Stephen JollesUniversity Hospital of Wales, Cardiff, UK.
Niall ConlonSt. James's Hospital, Dublin, Ireland.
Charu ChopraNHS Lothian, Edinburgh, UK.
Jennifer M TjonLeiden University Medical Centre, Leiden, The Netherlands.
Eleni TholouliManchester University NHS Foundation Trust, Manchester, UK.
Moira ThomasQueen Elizabeth University Hospital, Glasgow, UK.
Lisa DevlinRegional Immunology Service, Belfast, UK.
Claire StockdaleLeeds Hospitals NHS Trust, Leeds, UK.
Aarnoud HuissoonUniversity Hospitals Birmingham, Birmingham, UK.ORCID 0000-0002-1700-8661
Tor Henrik TvedtDepartment of Haematology, Oslo University Hospital, Oslo, Norway.
Elizabeth McDermottNottingham University Hospitals NHS Trust, Nottingham, UK.
Neill StorrarUniversity of Edinburgh, Edinburgh, UK.
Hannah HunterUniversity Hospitals Plymouth NHS Trust, Plymouth, UK.
Francesca FerruaPediatric Immunohematology and Bone Marrow Transplantation Unit, San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Harichandana GhantaUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK.
Olaf NethInstituto de Biomedicina de Sevilla, Seville, Spain.
Elisa CoderoDepartament of Medicine, Faculty of Medicine, Universidad de Sevilla, Seville, Spain.
Anoop MistryLeeds Hospitals NHS Trust, Leeds, UK.
Adrian ShieldsUniversity Hospitals Birmingham, Birmingham, UK.ORCID 0000-0001-5345-2156
Sarah GoddardBirmingham Heartlands Hospital, Birmingham, UK.
Arjan J KwakernaakAmsterdam University Medical Center, Amsterdam, The Netherlands.ORCID 0000-0002-5155-6581
Godelieve de BreeAmsterdam University Medical Center, Amsterdam, The Netherlands.
Franziska TaubeUniversitätsklinikum Carl Gustav Carus, Dresden, Germany.
Katja SockelUniversitätsklinikum Carl Gustav Carus, Dresden, Germany.
Julia KörholzUniversitätsklinikum Carl Gustav Carus, Dresden, Germany.
Carmen HerlingHospital for Children and Adolescents, Dresden, Germany.
Christian KlemannHospital for Children and Adolescents, Dresden, Germany.
Vikram SinghThe Clatterbridge Cancer Centre, Liverpool, UK.
Veronika DobsinskaNational Institute of Children's Diseases, Comenius University, Bratislava, Slovakia.
Sarah JohnstonNorth Bristol NHS Trust, Bristol, UK.ORCID 0000-0001-9324-4474
Prashantha VaitlaQueens Medical Centre, Nottingham, UK.
Samar OjaimiMonash Health, Melbourne, Australia.
Ravishankar SargurSheffield Teaching Hospitals, Sheffield, UK.
Shankara PaneeshaUniversity Hospitals Birmingham, Birmingham, UK.ORCID 0000-0002-7446-011X
Danielle BluntRoyal Adelaide Hospital/Adelaide University, Adelaide, Australia.
Carsten Schade-LarsenDept. of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Valérie MasseyHôpital du Sacré-Cœur de Montréal, Montreal, Canada.
Shreyans GandhiKings College Hospital NHS Foundation Trust, London, UK.
Mark KačarUniversity Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia.
Fredrik RorsmanUppsala University, Uppsala, Sweden.
Sinisa SavicUniversity of Leeds, Leeds, UK.
Arpad TothThe Clatterbridge Cancer Centre, Liverpool, UK.
Helen LeavisUniversity Medical Centre, Utrecht, The Netherlands.
Maria CarrabbaFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
Pavels GordinsHull University Teaching Hospitals NHS Trust, Hull, UK.
Sujoy KhanHull University Teaching Hospitals NHS Trust, Hull, UK.
Simon BulleyLeeds Hospitals NHS Trust, Leeds, UK.
Kiran TawanaCambridge University NHS Foundation Trust, Cambridge, UK.
Vanessa Daza-CajigalHospital Universitario Son Espases, Palma, Spain.
John SnowdenDivision of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK.ORCID 0000-0001-6819-3476
David M LoweRoyal Free London Hospitals NHS Foundation Trust, London, UK.
Sorena Kiani-AlikhanRoyal Free London Hospitals NHS Foundation Trust, London, UK.
Ben UttenthalCambridge University NHS Foundation Trust, Cambridge, UK.ORCID 0000-0002-5340-2527
Ariharan AnantharachaganLancashire Teaching Hospitals, Preston, UK.
Catharina SchuetzMedizinische Fakultät Carl Gustav Carus, TU Dresden, Dresden, Germany.
Smita Y PatelOxford University Hospitals NHS Foundation Trust, Oxford, UK.
Arian LaurenceDepartment of Haematology, University College London Hospitals NHS Foundation Trust, London, UK.ORCID 0000-0003-0942-8292
Siobhan O BurnsInstitute of Immunity & Transplantation, University College London, London, UK.
Venetia BigleyNewcastle Hospitals NHS Foundation Trust, Newcastle, UK.
Emma C MorrisInstitute of Immunity & Transplantation, University College London, London, UK. e.morris@ucl.ac.uk.ORCID 0000-0003-4834-1130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outcomes following international MDT assessment of adult IEI patients for allogeneic HSCT suggest early referral is vital: patients considered too high risk for transplant have poor outcomes with a 3-year overall survival of 31%.

Indexed as

Hematopoietic Stem Cell TransplantationAdultFemaleHumansMaleTime FactorsTransplantation, HomologousTreatment Outcome

Identifiers

PMID42432171
PMCPMC7619380

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.