Evidence map›Paper›PMID 42432167›Full record

ArticleNature ecology & evolution2026

Apparent stabilizing selection explains micro- and macroevolution of Drosophila wings.

Anneli Brändén, Stephen P De Lisle

Abstract read
In one paragraph

Article in Nature ecology & evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anneli BrändénDepartment of Environmental and Life Sciences, Karlstad University, Karlstad, Sweden.ORCID http://orcid.org/0009-0004-0174-6688
Stephen P De LisleDepartment of Environmental and Life Sciences, Karlstad University, Karlstad, Sweden. stephen.de.lisle@kau.se.ORCID http://orcid.org/0000-0001-9587-8665

Funding

Crafoordska Stiftelsen (Crafoord Foundation) 20220602Stiftelsen för Kunskaps- och Kompetensutveckling (Foundation for Knowledge and Development) 2024STGVetenskapsrådet (Swedish Research Council) 2019-03706Vetenskapsrådet (Swedish Research Council) 2024-04599
6 · The paper itself

Abstract

Evolution over deep time is often slow relative to neutral or directional expectations. A striking example is provided by Drosophila wing shape, which shows substantial genetic variance yet comparatively little macroevolutionary change. Here, using a large-scale fitness assay, we find pervasive stabilizing selection across dimensions of Drosophila melanogaster wing shape that is proportional to standing variation, driven by variance in male fitness and probably apparent selection generated by pleiotropy. Parameterizing a macroevolutionary Ornstein-Uhlenbeck model using our selection estimate recapitulates observed among-species variance under reasonable effective population sizes, suggesting a role for apparent stabilizing selection in constraining wing shape evolution over deep time.

Indexed as

Biological EvolutionDrosophila melanogasterSelection, GeneticWings, AnimalAnimalsFemaleGenetic FitnessMale

Identifiers

PMID42432167
PMCPMC13441934

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.