Evidence map›Paper›PMID 42432098›Full record

ArticleBritish dental journal2026

Ten-year trends in antimicrobial and analgesic prescribing by NHS dentists in England: a retrospective analysis study.

Nikul Patel, Noha Seoudi

Abstract read
In one paragraph

Article in British dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nikul PatelDepartment of Oral Microbiology, University Dental Hospital, Cardiff, United Kingdom. PatelN50@Cardiff.ac.uk.
Noha SeoudiInstitute of Dentistry, Queen Mary University of London, London, UK; Barts Health Dental Hospital, Barts Health NHS Trust, London, UK; College of Medicine and Dentistry Outreach Centre of Ulster University, Birmingham, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims Evidence on long-term National Health Service (NHS) dental prescribing is limited. This study aimed to identify whether utilisation of analgesics and antimicrobials returned to pre-Coronavirus Disease 2019 (COVID-19) levels in primary dental care, highlighting the national efforts needed to ensure patient safety when prescribing in dentistry.Methods Ten years of data from the NHS Business Services Authority on the utilisation of antimicrobials and analgesics by primary care dentists between January 2014 and December 2023 were obtained. Significant distributional changes were analysed using chi-square test, focusing on the impact of COVID-19 restrictions on prescribing.Results Total antimicrobial and analgesic prescribing returned to near pre-pandemic levels by December 2023 (antimicrobials - February 2020: 373.8, December 2023: 358 items/100,000; analgesics - February 2020: 8.78, December 2023: 8.35 items/100,000). Amoxicillin, metronidazole, erythromycin, paracetamol and diclofenac fell significantly versus peak (p <0.05). Clindamycin declined post-pandemic but remained above pre-pandemic levels (February 2020: 1.83, December 2023: 2.00 items/100,000). Dihydrocodeine comprised 42% of analgesics in December 2023 and exceeded pre-pandemic levels (February 2020: 3.22, December 2023: 3.51 items/100,000).Conclusions Prescribing guidelines and stewardship programs contributed to reduced antimicrobial use, though pandemic disruptions reversed progress. Relatively higher clindamycin prescribing raises concerns about Clostridioides difficile risk. Continued reliance on dihydrocodeine despite its side-effect profile highlights the importance of a national plan to ensure regular training and self-audit.

Indexed as

AnalgesicsAnti-Infective AgentsCOVID-19Drug PrescriptionsPractice Patterns, Dentists'EnglandHumansRetrospective StudiesState MedicineAnalgesicsAnti-Infective Agents

Identifiers

PMID42432098
PMCPMC13354529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.