ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026
Quantitative ventricular volume changes after endoscopic third ventriculostomy in children with Dandy-Walker malformation.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHydrocephalus occurs in up to 80% of children with Dandy-Walker malformation (DWM). Although endoscopic third ventriculostomy (ETV) is increasingly used as a primary treatment, quantitative data regarding changes in ventricular and posterior fossa cyst volumes remain limited. We evaluated volumetric changes following ETV and correlated them with clinical outcomes.
methodsThis retrospective study included children with DWM who underwent primary ETV for hydrocephalus between 2015 and 2024. Patients with a history of shunting or secondary fourth ventricular outlet obstruction were excluded. Preoperative and 3-month postoperative MRI scans were analyzed using semiautomated volumetry. Total supratentorial ventricular volume (V1) and posterior fossa cyst volume (V2) were calculated. Clinical improvement, stoma patency, and need for re-intervention were assessed.
resultsThirty children (23 boys; 40% < 1 year) underwent ETV with a mean follow-up of 30.6 months. The overall success rate was 66.7%, with most failures occurring within four months. Paired volumetric analysis was available in 10 patients. Mean supratentorial ventricular volume decreased significantly from 708.7 ± 411.2 cc preoperatively to 550.4 ± 361.3 cc postoperatively (mean reduction 25.2%; p = 0.004). Posterior fossa cyst volume decreased from 173.0 ± 164.7 cc to 153.0 ± 168.1 cc (mean reduction 19.2%; p = 0.016), though reduction was inconsistent. Ventricular volume reduction correlated and CSF flow across the stoma with good clinical outcomes, whereas cyst volume reduction did not consistently predict clinical improvement.
conclusionETV provides effective shunt-free treatment for hydrocephalus in majority DWM patients. Reduction in supratentorial ventricular volume correlates with clinical success, while posterior fossa cyst regression appears variable and not essential for a favorable outcome.
Indexed as
Identifiers
42432063What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.