Evidence map›Paper›PMID 42431926›Full record

ArticleNPJ Parkinson's disease2026

Home-based deep sleep modulation in Parkinson's disease: extension study on long-term feasibility and sleep-related outcomes.

Jana Horlacher, Nora-Hjördis Moser, Simon J Schreiner, Renske Sassenburg, Lydia Kämpf, Sophia D Schibler, Valentino Mutschler, Esther Werth, Philipp Valko, Jelena Skorucak and 5 more

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Article in NPJ Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jana HorlacherDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Nora-Hjördis MoserDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Simon J SchreinerDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Renske SassenburgDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Lydia KämpfDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Sophia D SchiblerDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Valentino MutschlerDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Esther WerthDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Philipp ValkoDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Jelena SkorucakDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Laura FersterDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Walter KarlenInstitute of Biomedical Engineering, Ulm University, Ulm, Germany.
Reto HuberCenter of Competence Sleep & Health Zurich, University of Zurich, Zurich, Switzerland.
Christian R BaumannDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Angelina MaricDepartment of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland. angelina.maric@usz.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study assessed feasibility and effects of a randomised two-week, at-home intervention with phase-targeted auditory stimulation (PTAS) of slow waves in Parkinson's disease (PD). We reproduced previously reported enhancement of slow wave activity and confirmed indications of improved patient-reported outcomes. Together with the high adherence and data quality, this suggests that home-based PTAS protocols are a feasible method for investigating the long-term therapeutic potential of deep sleep enhancement in PD.

Identifiers

PMID42431926
PMCPMC13645807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.