Evidence map›Paper›PMID 42430851›Full record

ReviewCurrent opinion in microbiology2026

The polar landscape of bacterial pathogens and predators.

Trung Nguyen, Erin D Goley

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Trung NguyenDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States.
Erin D GoleyDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States. Electronic address: egoley1@jhmi.edu.

Funding

Local and global regulation of bacterial growthR35GM136221 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Erin D Goley · 2020 to 2026
$3.0M
Generation and characterization of a large-scale transposon mutant library of Rickettsia parkeriR61AI179998 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Erin D Goley · 2024 to 2026
$844k
Cell polarity in the obligate intracellular pathogen Rickettsia parkeriR21AI196675 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Erin D Goley · 2026 to 2026
$423k
NIAID NIH HHS R21 AI196675NIAID NIH HHS R61 AI179998NIGMS NIH HHS R35 GM136221
6 · The paper itself

Abstract

Precise spatial positioning of cellular constituents is critical for bacterial replication, interactions, and behavior. Rod-shaped bacteria may concentrate molecules and machinery at the cell poles, often by leveraging polar scaffolding proteins to recruit other factors. These typically small proteins can self-assemble into higher-order structures that provide platforms to direct fundamental processes like chromosome segregation, division plane selection, and differentiation. Beyond fundamental cellular processes, polarity is implicated in a wide range of bacterial behaviors, including environmental sensing, intercellular interactions, and motility. In this review, we describe polarity-determining factors and their cellular functions specifically in bacterial predators and in host-associated bacteria, including plant and human pathogens. We aim to highlight pivotal roles cell polarity plays in promoting fitness vis-à-vis the host-microbe and microbe-microbe interface.

Indexed as

BacteriaBacterial Physiological PhenomenaCell PolarityHost-Pathogen InteractionsBacterial ProteinsHumansBacterial Proteins

Identifiers

PMID42430851
PMCPMC13360999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.