Evidence map›Paper›PMID 42430468›Full record

ArticleScience advances2026

Periodic shifts in viral load increase risk of Hendra virus spillover from

Tamika J Lunn, Benny Borremans, Devin N Jones-Slobodian, Maureen K Kessler, Adrienne S Dale, Claude K Yinda, Manuel Ruiz-Aravena, Caylee A Falvo, Daniel E Crowley, James O Lloyd-Smith and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Tamika J LunnOdum School of Ecology, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0003-4439-2045
Benny BorremansWildlife Health Ecology Research Organization, San Diego, CA 92107, USA.ORCID 0000-0002-7779-4107
Devin N Jones-SlobodianDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59715, USA.ORCID 0000-0001-9215-2930
Maureen K KesslerDepartment of Ecology, Montana State University, Bozeman, MT 59715, USA.ORCID 0000-0001-5380-5281
Adrienne S DaleDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0001-8991-4308
Claude K YindaLaboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.ORCID 0000-0002-5195-5478
Manuel Ruiz-AravenaDepartment of Wildlife, Fisheries and Aquaculture, Mississippi State University, Starkville, MS 39759, USA.ORCID 0000-0001-8463-7858
Caylee A FalvoDepartment of Public and Ecosystem Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-1520-137X
Daniel E CrowleyDepartment of Public and Ecosystem Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-4262-253X
James O Lloyd-SmithDepartment of Ecology and Evolutionary Biology, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-7941-502X
Vincent J MunsterLaboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.ORCID 0000-0002-2288-3196
Peggy EbyCentre for Planetary Health and Food Security, Griffith University, Nathan, QLD 4111, Australia.ORCID 0000-0001-5441-2682
Hamish McCallumCentre for Planetary Health and Food Security, Griffith University, Nathan, QLD 4111, Australia.ORCID 0000-0002-3493-0412
Peter HudsonCenter for Infectious Disease Dynamics, Pennsylvania State University, State College, PA 16801, USA.
Olivier RestifDepartment of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.ORCID 0000-0001-9158-853X
Liam P McGuireDepartment of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada.ORCID 0000-0002-5690-0804
Ina L SmithHealth and Biosecurity Business Unit, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Canberra, ACT 2601, Australia.ORCID 0000-0001-5807-3737
Bat One Health Group Collaborators
Raina K PlowrightDepartment of Public and Ecosystem Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-3338-6590
Alison J PeelCentre for Planetary Health and Food Security, Griffith University, Nathan, QLD 4111, Australia.ORCID 0000-0003-3538-3550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prediction and management of zoonotic spillover requires an understanding of infection dynamics within reservoir host populations. Spillover risk is commonly inferred from infection prevalence based on detection of viral genomic material, yet detection alone does not indicate the presence of infectious virus or a sufficient dose for transmission. We undertook a comprehensive investigation of Hendra virus shedding in its primary reservoir,

Indexed as

ChiropteraHendra VirusHenipavirus InfectionsViral LoadAnimalsDisease ReservoirsHorsesPrevalenceRNA, ViralVirus SheddingRNA, Viral

Identifiers

PMID42430468
PMCPMC13353404

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.