Evidence map›Paper›PMID 42430425›Full record

ArticlePLoS computational biology2026

Systems biology during 20 years of PLoS Computational Biology.

Mark Alber, Marc R Birtwistle, Stacey D Finley, Pedro Mendes

Abstract read
In one paragraph

Article in PLoS computational biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mark AlberDepartment of Mathematics and Interdisciplinary Center for Data-driven Modeling in Biology, University of California, Riverside, Riverside, California, United States of America.
Marc R BirtwistleDepartment of Chemical and Biomolecular Engineering, Clemson University, Clemson, South Carolina, United States of America.
Stacey D FinleyDepartments of Biomedical Engineering and Quantitative & Computational Biology, University of Southern California, Los Angeles, California, United States of America.ORCID https://orcid.org/0000-0001-6901-3692
Pedro MendesCenter for Cell Analysis and Modeling, University of Connecticut School of Medicine, Farmington, Connecticut, United States of America.ORCID https://orcid.org/0000-0001-6507-9168

Funding

Mechanistic Modeling of Cellular SystemsR24GM137787 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Pedro Mendes, Ion I. Moraru · 2020 to 2026
$8.9M
Modeling based design of chimeric antigen receptors for Natural Killer cell-based immunotherapyU01CA275808 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINLEY, STACEY DELERIA, GRAHAM, NICHOLAS ALEXANDER · 2022 to 2025
$2.5M
Mechanistic Pharmacodynamic Modeling for Drug Combination ResponsesR35GM141891 · NIGMS · CLEMSON UNIVERSITY · PI BIRTWISTLE, MARC R. · 2021 to 2025
$2.1M
Cell State Network-Directed TherapyU01CA290442 · NCI · CLEMSON UNIVERSITY · PI Marc R. Birtwistle, James M. Gallo · 2024 to 2026
$1.6M
Exploring the dynamic tumor-immune ecosystem of breast cancer in heterogeneous tumor microenvironmentsU01CA293859 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Stacey Deleria Finley, Evanthia Theodosiou Roussos Torres · 2025 to 2026
$1.1M
NCI NIH HHS U01 CA275808NCI NIH HHS U01 CA290442NCI NIH HHS U01 CA293859NIGMS NIH HHS R24 GM137787NIGMS NIH HHS R35 GM141891
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42430425
PMCPMC13354084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.