A Structurally Analogous Series of Mn(II), Fe(II), and Co(II) Complexes Which Exhibit Three Distinct Reactivities with Dioxygen.

Vishal Yadav, Lyupeng Wen, Sudha Yadav, Isabella Niedzwiecki, Maxime A Siegler, David P Goldberg

Abstract read

In one paragraph

Article in Inorganic chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vishal YadavDepartment of Chemistry, the Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland21218, United States.ORCID 0000-0002-7016-2991

Lyupeng WenDepartment of Chemistry, the Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland21218, United States.ORCID 0000-0002-4086-8096

Sudha YadavDepartment of Chemistry, the Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland21218, United States.

Isabella NiedzwieckiDepartment of Chemistry, the Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland21218, United States.

Maxime A SieglerDepartment of Chemistry, the Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland21218, United States.ORCID 0000-0003-4165-7810

David P GoldbergDepartment of Chemistry, the Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland21218, United States.ORCID 0000-0003-4645-1045

Funding

Synthetic Nonheme Iron O2 Activation and S-OxygenationR01GM119374 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GOLDBERG, DAVID P · 2016 to 2023

$3.2M

Heme and Nonheme Transition Metal Complexes, Reactivity, and MechanismR35GM149233 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI David P Goldberg · 2023 to 2026

$2.1M

NIGMS NIH HHS 1R35GM149233NIGMS NIH HHS R01 GM119374NIGMS NIH HHS R35 GM149233NIGMS NIH HHS RO1GM119374

6 · The paper itself

Abstract

The synthesis and characterization of a series of nonheme Fe(II), Mn(II), and Co(II) complexes, MII(BNPAPh2O)(Cl) (M = Fe, Mn, Co), are reported. These complexes were characterized using single-crystal X-ray crystallography, 1H NMR spectroscopy, and ATR-FTIR spectroscopy to establish their structural and electronic properties. Their reactivity with dioxygen revealed distinct metal-dependent pathways. The Mn(II) complex undergoes ligand-based C-N bond cleavage, forming a pentanuclear cluster, whereas the Fe(II) complex reacts with O2 to generate a well-defined FeIII(BNPAPh2O)(OH)(Cl) species, relevant to the rebound intermediate in nonheme iron halogenases. In contrast, the Co(II) complex exhibits no detectable reactivity toward O2. These differences illuminate the intrinsic metal-dependent factors that govern O2 activation and underscore the central role of metal identity in tuning reactivity and selectivity in bioinorganic oxidation chemistry.

Identifiers

PMID42430371

DOI10.1021/acs.inorgchem.6c00864

PMCPMC13364098

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.