Evidence map›Paper›PMID 42430018›Full record

Trial reportNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026

Efficacy and safety of immersive, sEMG-triggered virtual reality game training for post-stroke dysphagia: a randomized, single-blind, controlled trial.

Xinfang Kang, Wentao Rao, Ruhui Yang, Bofan Chen, Qi Xiao, Yining Xie, Fangzhen Lin, Yuxin Zhan, Haimin Zeng, Xiang Chen

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinfang Kang *Department of Rehabilitation Medicine, Jiangxi Maternal and Child Health Hospital, Nanchang, China.
Wentao Rao *Department of Trauma Emergency Center, Ganzhou People's Hospital, Ganzhou, Jiangxi Province, 341000, China.
Ruhui YangDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1 MinDe Road, Nanchang, Jiangxi, 330006, China.
Bofan ChenDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1 MinDe Road, Nanchang, Jiangxi, 330006, China.
Qi XiaoDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1 MinDe Road, Nanchang, Jiangxi, 330006, China.
Yining XieDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1 MinDe Road, Nanchang, Jiangxi, 330006, China.
Fangzhen LinDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1 MinDe Road, Nanchang, Jiangxi, 330006, China.
Yuxin ZhanDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1 MinDe Road, Nanchang, Jiangxi, 330006, China.
Haimin ZengDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1 MinDe Road, Nanchang, Jiangxi, 330006, China. zenghaimin0125@163.com.
Xiang ChenDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1 MinDe Road, Nanchang, Jiangxi, 330006, China. chenxiangteam2025@163.com.ORCID http://orcid.org/0009-0009-7380-0985

Funding

Clinical Research Project of the Second Affiliated Hospital of Nanchang University 2024efyA01the Doctoral Start-up Fund B3477the Innovation and Entrepreneurship Training Program for College Students in Jiangxi Province S202410403035the Nanchang University Medical Interdisciplinary Innovation Fund Project 2024JC002the Nanchang University Second Affiliated Hospital In-Hospital Project 2023efyC02the National College Students' Innovative Entrepreneurial Training Plan Program 202410403067the National Natural Science Foundation of China Incubation Project 2023YNFY12009
6 · The paper itself

Abstract

backgroundPost-stroke dysphagia (PSD) is a common and serious complication. Traditional rehabilitation for PSD is often hampered by low patient adherence due to its unengaging nature. This study aimed to evaluate the efficacy and safety of an immersive, surface electromyography (sEMG)-triggered virtual reality (VR) game training as an adjunctive therapy for patients with PSD.

methodsIn this prospective, randomized, single-blind, controlled trial, 60 patients with PSD were randomly assigned to an experimental group (n = 30) or a control group (n = 30). The control group received conventional swallowing therapy, while the experimental group received the same therapy plus sEMG-triggered immersive VR game training. Treatment was provided 5 times per week for 3 weeks. Outcomes included the Kubota Water Swallowing Test (WST), Standardized Swallowing Assessment (SSA), Functional Oral Intake Scale (FOIS), and sEMG root mean square (RMS) values.

resultsAfter 3 weeks, both groups showed significant improvement, with lower WST grades and SSA scores and higher FOIS levels and sEMG RMS values (all P < 0.05). The experimental group achieved significantly greater gains in WST, SSA, FOIS, and RMS values than the control group (all P < 0.05). The total effective rate was 86.67% in the experimental group and 73.33% in the control group, and the distribution of clinical efficacy categories differed significantly between the two groups (Z = 3.15, P = 0.002). No serious training-related adverse events occurred.

conclusionsImmersive, sEMG-triggered VR game training may be a safe and effective adjunct to conventional swallowing therapy for improving short-term swallowing-related outcomes in patients with PSD.

Indexed as

Deglutition DisordersElectromyographyStrokeStroke RehabilitationVideo GamesVirtual RealityAgedFemaleHumansMaleMiddle AgedProspective StudiesSingle-Blind MethodTreatment OutcomeBiofeedbackPost-stroke dysphagiaRandomized controlled trialSurface electromyographyVirtual reality

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.