Evidence map›Paper›PMID 42429951›Full record

ArticleDie Ophthalmologie2026

[Choroidal folds as a diagnostic indication for a posterior mass of unknown etiology].

Zaynab Khattabi, Berthold Seitz, Nikolaos E Bechrakis, Tobias Kiefer

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In one paragraph

Article in Die Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zaynab KhattabiKlinik für Augenheilkunde, Universitätsklinikum des Saarlandes (UKS), Kirrberger Str., 66424, Homburg/Saar, Deutschland. zaynab.khattabi@uks.eu.
Berthold SeitzKlinik für Augenheilkunde, Universitätsklinikum des Saarlandes (UKS), Kirrberger Str., 66424, Homburg/Saar, Deutschland.
Nikolaos E BechrakisKlinik für Augenheilkunde, Universitätsklinikum Essen, Essen, Deutschland.
Tobias KieferKlinik für Augenheilkunde, Universitätsklinikum Essen, Essen, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 59-year-old woman presented with a four-month history of progressive visual loss and floaters in her left eye. Her medical history included hypothyroidism, psoriasis, and type 2 diabetes. Fundus examination revealed choroidal folds, an amelanotic lesion temporal to the fovea, and an exudative retinal detachment. Optical coherence tomography (OCT) demonstrated a choroidal mass without subretinal fluid, while indocyanine green angiography (ICGA) showed a hypocyanescent lesion with no intrinsic vascularity. B-scan ultrasonography revealed an inhomogeneous choroidal mass with retrobulbar fluid (positive T-sign). Blood tests revealed elevated C-reactive protein (CRP) and liver enzymes levels, together with positive antinuclear antibodies (ANA), while the chest X-ray was normal. The overall clinical and imaging findings were consistent with nodular granulomatous scleritis. Choroidal melanoma, uveal lymphoma, primary vitreoretinal lymphoma, and choroidal hemangioma were excluded based on their imaging characteristics. Treatment with systemic corticosteroids resulted in rapid visual improvement and complete resolution of the lesion. This case demonstrates how inflammatory choroidal lesions can mimic intraocular tumors. Recognizing characteristic multimodal imaging features (choroidal folds, preserved choroidal vasculature on ICGA, positive T-sign on ultrasonography) can enable a confident diagnosis without biopsy, avoiding unnecessary treatment and delays in cancer diagnosis.

Indexed as

Choroid DiseasesScleritisDiagnosis, DifferentialFemaleFluorescein AngiographyHumansMiddle AgedTomography, Optical CoherenceChoroidMultimodal imagingScleritisTumorUveitis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.