Trial reportNeural plasticity2026
The Efficacy of Individualized Music Therapy in Patients With MCS: A Pilot Study on EEG.
Trial report in Neural plasticity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Efficacy of Individualized Music Therapy in Patients With MCS: A Pilot Study on EEG.Neural plasticity · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectiveTo evaluate the feasibility, safety, and preliminary effects of individual music therapy (IMT) on electroencephalography (EEG) cortical activation in patients with minimally conscious state (MCS).
designThis study was pilot randomized, single-blind, and blank-controlled trial.
settingChina Rehabilitation Research Center (CRRC), Beijing, China.
participantsSixty-two MCS patients (diagnosed by Coma Recovery Scale-Revised [CRS-R]) were enrolled between March 2024 and July 2025; 43 completed the trial and were randomized.
interventionThe experimental group (n = 22) received 12-week individualized music therapy (30-min sessions, five times per week) delivered by a certified music therapist. COMPARATOR: The control group (n = 21) received routine treatment and rehabilitation training without music intervention. PRIMARY OUTCOME: The change in EEG spectral power (alpha band, 8-13 Hz) over right-hemisphere frontocentral regions from baseline (T1) to post-intervention (T2).
resultsThe IMT group showed significantly increased alpha power over the right lateral prefrontal cortex, precentral gyrus, and central sulcus at T2 compared T1 (p < 0.05; descriptive comparison), whereas no such change was observed in the control group. No adverse events occurred in either group.
conclusionIMT is feasible and safe in medically fragile MCS patients and may induce right-hemisphere cortical activation. These pilot findings are hypothesis-generating and require confirmation in larger, adequately powered trials.
trial registrationChinese Clinical Trial Registry: ChiCTR2500114153, MR-11-24-014167.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.