ArticleAlcohol, clinical & experimental research2026
Trends in Alcohol-Related Deaths in the United States Over 55 Years: 1968-2023.
Article in Alcohol, clinical & experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAlcohol consumption is a leading cause of preventable mortality worldwide. We examined long-term trends in alcohol-related deaths in the United States over 55 years (1968-2023) and analyzed demographic disparities.
methodsUsing CDC WONDER data, we identified alcohol-related deaths among adults aged ≥ 25 years. Age-adjusted mortality rates (AAMRs) per 100,000 population were calculated, and joinpoint regression analyzed temporal trends by sex, race, age, and geographic region.
resultsFrom 1968 to 2023, 1,321,804 alcohol-related deaths occurred. AAMRs increased from 13.1 to 19.3 (AAPC: 0.7, p < 0.001), with a sharp acceleration during 2018-2021 (APC: 14.1) followed by a decline during 2021-2023 (APC: -6.9). Males consistently had higher mortality than females, though the gender gap narrowed. A striking racial inversion occurred: mortality among Black individuals declined from 27.7 to 13.5 (AAPC: -1.4), while mortality among White individuals increased from 11.3 to 21.1 (AAPC: 1.1) with older adults (65+) showing the steepest long-term increase (AAPC: 1.4). Regionally, the Midwest experienced the greatest rise in mortality (AAPC: 1.4), while the Northeast remained stable.
conclusionsAlcohol-related mortality has increased substantially over 55 years, with profound demographic shifts including a complete racial disparity inversion and narrowing gender gap. Recent declines (2021-2023) offer cautious optimism, but sustained, targeted interventions are needed for high-risk populations.
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