Evidence map›Paper›PMID 42429186›Full record

ArticleActa crystallographica. Section F, Structural biology communications2026

Crystal structure of Legionella pneumophila glycosidase effector LegY.

Jing Chen, Fan Li, Shao Yuan Wang, Tao Tao Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing ChenFujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Department of Hematology, Fujian Medical University Union Hospital, Xinquan Road, Fuzhou City, Fujian Province, Fuzhou 350001, People's Republic of China.
Fan LiKey Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, The Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, College of Life Sciences, Fujian Normal University, Fuzhou 350117, People's Republic of China.
Shao Yuan WangFujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Department of Hematology, Fujian Medical University Union Hospital, Xinquan Road, Fuzhou City, Fujian Province, Fuzhou 350001, People's Republic of China.
Tao Tao ChenKey Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, The Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, College of Life Sciences, Fujian Normal University, Fuzhou 350117, People's Republic of China.

Funding

Fujian Medical University 2023QH1028Fujian Provincial Clinical Research Center for Hematological Malignancies 2020Y2006Fujian Provincial Health Technology Project 2025QNA018Joint Funds for the Innovation of Science and Technology, Fujian Province 2024Y9086National Key Clinical Specialty Discipline Construction Program of China 2021-76Natural Science Foundation of Fujian Province 2025J01639
6 · The paper itself

Abstract

Legionella pneumophila translocates approximately 330 effectors into host cells via its type IVB secretion system. These effectors mediate a diverse array of post-translational modifications, among which reversible glycosylation is closely associated with bacterial virulence. Although several glycosyltransferase effectors have been identified that glycosylate host proteins to subvert host cellular processes, no glycosidase effector has been reported to date. Here, we report the crystal structure of LegY, a putative glycosidase effector from L. pneumophila, determined to 1.46 Å resolution (PDB entry 27xj). LegY adopts a single-domain (α/α)

Indexed as

Bacterial ProteinsGlycoside HydrolasesLegionella pneumophilaAmino Acid SequenceCrystallography, X-RayModels, MolecularPhylogenyBacterial ProteinsGlycoside Hydrolasesbacterial toxinsconvergent evolutionGH15 familyglycosidasesLegionella pneumophila

Identifiers

PMID42429186
PMCPMC13431054

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.