Evidence map›Paper›PMID 42429022›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Metabolic Labeling and Visualization of Isoprenoids Using Alkyne-Modified DMAPP Analogs in Bacillus subtilis.

Zackary N Hulsey, Dillon P McBee, Claudia L Dolan, Francis M Rossi, Neil A Truslow, Allyson R Taylor, Thomas N Trybala, Joshua A Baccile

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zackary N HulseyDepartment of Chemistry, University of Tennessee, Knoxville, USA.ORCID 0009-0008-2266-7881
Dillon P McBeeDepartment of Chemistry, University of Tennessee, Knoxville, USA.
Claudia L DolanDepartment of Chemistry, University of Tennessee, Knoxville, USA.
Francis M RossiDepartment of Chemistry, SUNY Cortland Cortland, New York, USA.
Neil A TruslowDepartment of Chemistry, University of Tennessee, Knoxville, USA.
Allyson R TaylorDepartment of Chemistry, University of Tennessee, Knoxville, USA.
Thomas N TrybalaDepartment of Chemistry, University of Tennessee, Knoxville, USA.
Joshua A BaccileDepartment of Chemistry, University of Tennessee, Knoxville, USA.ORCID 0000-0003-4334-755X

Funding

Integrated Membrane Program (IMP)T32GM142621 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI REYNOLDS, TODD B · 2021 to 2025
$1.4M
Elucidation of the chemical and biological roles of five-carbon metabolismR35GM157211 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI Joshua A Baccile · 2025 to 2026
$706k
National Science Foundation CHE-2204170NIGMS NIH HHS R35 GM157211NIGMS NIH HHS T32 GM142621NIH HHS 1R35GM157211-01NIH HHS 1 T32 GM142621
6 · The paper itself

Abstract

Isoprenoids are a chemically and functionally diverse class of metabolites that underlie essential bacterial physiology including respiration and cell envelope biogenesis. Chemical interrogation of isoprenoid metabolism remains limited because the two central five-carbon (C

Indexed as

AlkynesBacillus subtilisHemiterpenesOrganophosphorus CompoundsTerpenes3,3-dimethylallyl pyrophosphateAlkynesHemiterpenesisopentenyl pyrophosphateOrganophosphorus CompoundsTerpenesBacillus subtilisbiochemistrybiogenesisbioorthogonal chemistrychemistryisopentenyl pyrophosphateprenylationpyrophosphateterpenoid

Identifiers

PMID42429022
PMCPMC13502626

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.