ArticleACS omega2026
Free-Electron Laser-Based Extended Wide-Field Mid-Infrared Photothermal Imaging for Biomedical and Microplastic Analysis.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Evaluation of filter substrates for concurrent optical photothermal infrared and Raman spectroscopy in microplastic analysis.Analytical and bioanalytical chemistry · 2026Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wide-field mid-infrared photothermal (MIP) imaging offers rapid label-free chemical contrast for biomedical and polymer analysis. Its field of view (FOV) depends on the mid-infrared pump power of infrared lasers. Here, a wide-field MIP microscope is presented using up to 150 nJ pulse energies of a free-electron laser (FEL) as the pump source to achieve a larger FOV compared to a quantum cascade laser (QCL) excitation with typically 1 nJ pulses. Both implementations use counter-propagating beam paths with a microsecond pulsed 450 nm LED as the probe source and a CMOS camera that records images using a virtual lock-in detection scheme. FEL's higher pulse power expands the FOV by approximately a factor of 20, enabling submicron-resolution wide-field MIP imaging of polystyrene beads, single cells, and a murine brain tissue section. QCL systems with less intense pump pulses achieve only 45 μm FOV for samples including polystyrene beads,
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Registered trials
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